Phototautomerization of cytosine derivatives on ultra-violet irradiation1

Phototautomerization of cytosine derivatives on ultra-violet irradiation1

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ABSTRACT UNSTABLE products were formed from certain cytosine derivatives on ultra-violet irradiation. These products had a new band at ∼240 mµ and lacked the characteristic ∼270 mµ maxima of cytosine derivatives. The products were not only reconstituted to their original compounds in the presence of acid and base but also spontaneously reconstituted themselves on standing, as indicated by the reversion of the ultra-violet spectra2. Therefore, in these respects the cytosines differ from the uracils1,8. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS A CAUTIONARY TALE OF BASIC AZO PHOTOSWITCHING IN DICHLOROMETHANE FINALLY EXPLAINED Article Open access 01 November 2024 PHOTOBIOCHEMICAL MECHANISMS OF BIOMOLECULES RELEVANT TO GERMICIDAL ULTRAVIOLET IRRADIATION AT 222 AND 254 NM Article Open access 29 October 2022 BREAKING THE DNA BY SOFT X-RAYS IN THE WATER WINDOW REVEALS THE SCAVENGING AND TEMPORAL BEHAVIOUR OF ·OH RADICALS Article Open access 18 November 2024 REFERENCES * Part I of this series, _J. Amer. Chem. Soc._, 80, 6196 (1958); Part II, _ibid._, 80, 6199 (1958); also _ibid._, 78, 4180 (1956). * Sinsheimer, R. L., _Radiation Res._, 6, 121 (1957). Wierzchowski, K. L., and Shugar, D., _Biochim. Biophys. Acta_, 25, 355 (1957). Article  ADS  CAS  Google Scholar  * Marshall, J. R., and Walker, J., _J. Chem. Soc._, 1004 (1951). Brown, D. J., Hoerger, E., and Mason, S. F., _ibid._, 211 (1955). * Wang, S. Y., _Nature_ (in the press). * Batt, R. D., Martin, J. K., Ploeser, J. McT., and Murray, J., _J. Amer. Chem. Soc._, 76, 3663 (1954). Article  CAS  Google Scholar  * Fox, J. J., and Shugar, D., _Bull. Soc. Chim. Belg._, 61, 44 (1952). Article  CAS  Google Scholar  * Shugar, D., and Fox, J. J., _Biochim. Biophys. Acta_, 9, 199 (1952). Article  CAS  Google Scholar  * Moore, A. M., and Thomas, C. H., _Science_, 122, 594 (1955); _Can. J. Chem._, 35, 163 (1957). Article  ADS  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Physiology Department, Tufts University School of Medicine, Boston, 11, Massachusetts SHIH YI WANG Authors * SHIH YI WANG View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE WANG, S. Phototautomerization of Cytosine Derivatives on Ultra-violet Irradiation1 . _Nature_ 184, 184–185 (1959). https://doi.org/10.1038/184184a0 Download citation * Issue Date: 18 July 1959 * DOI: https://doi.org/10.1038/184184a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT UNSTABLE products were formed from certain cytosine derivatives on ultra-violet irradiation. These products had a new band at ∼240 mµ and lacked the characteristic ∼270 mµ maxima of


cytosine derivatives. The products were not only reconstituted to their original compounds in the presence of acid and base but also spontaneously reconstituted themselves on standing, as


indicated by the reversion of the ultra-violet spectra2. Therefore, in these respects the cytosines differ from the uracils1,8. Access through your institution Buy or subscribe This is a


preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per


year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during


checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS A CAUTIONARY TALE OF


BASIC AZO PHOTOSWITCHING IN DICHLOROMETHANE FINALLY EXPLAINED Article Open access 01 November 2024 PHOTOBIOCHEMICAL MECHANISMS OF BIOMOLECULES RELEVANT TO GERMICIDAL ULTRAVIOLET IRRADIATION


AT 222 AND 254 NM Article Open access 29 October 2022 BREAKING THE DNA BY SOFT X-RAYS IN THE WATER WINDOW REVEALS THE SCAVENGING AND TEMPORAL BEHAVIOUR OF ·OH RADICALS Article Open access


18 November 2024 REFERENCES * Part I of this series, _J. Amer. Chem. Soc._, 80, 6196 (1958); Part II, _ibid._, 80, 6199 (1958); also _ibid._, 78, 4180 (1956). * Sinsheimer, R. L., _Radiation


Res._, 6, 121 (1957). Wierzchowski, K. L., and Shugar, D., _Biochim. Biophys. Acta_, 25, 355 (1957). Article  ADS  CAS  Google Scholar  * Marshall, J. R., and Walker, J., _J. Chem. Soc._,


1004 (1951). Brown, D. J., Hoerger, E., and Mason, S. F., _ibid._, 211 (1955). * Wang, S. Y., _Nature_ (in the press). * Batt, R. D., Martin, J. K., Ploeser, J. McT., and Murray, J., _J.


Amer. Chem. Soc._, 76, 3663 (1954). Article  CAS  Google Scholar  * Fox, J. J., and Shugar, D., _Bull. Soc. Chim. Belg._, 61, 44 (1952). Article  CAS  Google Scholar  * Shugar, D., and Fox,


J. J., _Biochim. Biophys. Acta_, 9, 199 (1952). Article  CAS  Google Scholar  * Moore, A. M., and Thomas, C. H., _Science_, 122, 594 (1955); _Can. J. Chem._, 35, 163 (1957). Article  ADS 


CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Physiology Department, Tufts University School of Medicine, Boston, 11, Massachusetts SHIH YI WANG


Authors * SHIH YI WANG View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS


ARTICLE WANG, S. Phototautomerization of Cytosine Derivatives on Ultra-violet Irradiation1 . _Nature_ 184, 184–185 (1959). https://doi.org/10.1038/184184a0 Download citation * Issue Date: 18


July 1959 * DOI: https://doi.org/10.1038/184184a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link


is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative