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ABSTRACT THE basic question of whether primary human malignant tumours consist of euploid or aneuploid cells has so far remained unanswered. It has been possible to determine the chromosome
complement and deoxyribonucleic acid content only of human carcinomas with cells exfoliated in ascitic fluid1,2, human carcinomas transplanted in rats and hamsters3 and carcinomas grown in
tissue culture.4,5 This lack of information can be attributed to several technical difficulties. Chromosome counts on solid human tumours cannot be generally obtained since a pretreatment
with colchicine is impossible. The deoxy ribonucleic acid measurement by the one-wave-length method has so far been limited to interphase nuclei6 in which the occurrence of deoxyribonucleic
acid synthesis prevents any conclusions in regard to euploidy or aneuploidy. Access through your institution Buy or subscribe This is a preview of subscription content, access via your
institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this
article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in
* Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS ANEUPLOIDY AS A PROMOTER AND SUPPRESSOR OF MALIGNANT GROWTH
Article 11 January 2021 NORMAL BREAST TISSUES HARBOUR RARE POPULATIONS OF ANEUPLOID EPITHELIAL CELLS Article 20 November 2024 CLONAL ORIGIN AND DEVELOPMENT OF HIGH HYPERDIPLOIDY IN CHILDHOOD
ACUTE LYMPHOBLASTIC LEUKAEMIA Article Open access 25 March 2023 REFERENCES * Ising, V., and Levan, A., _Acta, path. microbiol. Scand._, 40, 13 (1957). CAS Google Scholar *
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(1959). Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Saskatchewan Research Unit of the National Cancer Institute of Canada, and Department of Cancer
Research, University of Saskatchewan, H. F. STICH * Department of Pathology, University Hospital, University of Saskatchewan, Saskatoon, Sask H. E. EMSON Authors * H. F. STICH View author
publications You can also search for this author inPubMed Google Scholar * H. E. EMSON View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND
PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE STICH, H., EMSON, H. Aneuploid Deoxyribonucleic Acid Content of Human Carcinomas. _Nature_ 184, 290–291 (1959).
https://doi.org/10.1038/184290a0 Download citation * Issue Date: 25 July 1959 * DOI: https://doi.org/10.1038/184290a0 SHARE THIS ARTICLE Anyone you share the following link with will be able
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