Fundamental theorem of natural selection

Fundamental theorem of natural selection

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ABSTRACT LI1 has pointed out, by means of a neat algebraic formulation, that Fisher's fundamental theorem of natural selection does not apply exactly in a discrete-generation random-mating situation unless there is no dominance in fitness, and that the mean fitness cannot decrease from generation to generation for a single diallelic locus. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS POLYGENIC ADAPTATION: A UNIFYING FRAMEWORK TO UNDERSTAND POSITIVE SELECTION Article 29 June 2020 IDIOSYNCRATIC EPISTASIS CREATES UNIVERSALS IN MUTATIONAL EFFECTS AND EVOLUTIONARY TRAJECTORIES Article 07 September 2020 CORRELATIONAL SELECTION IN THE AGE OF GENOMICS Article 15 April 2021 REFERENCES * Li, C. C., _Nature_, 214, 505 (1967). Article  ADS  CAS  Google Scholar  * Fisher, R. A., _The Genetical Theory of Natural Selection_ (first ed.) (Oxford Univ. Press, 1930). Book  Google Scholar  * Fisher, R. A., _Ann. Eugen._, 11, 53 (1941). Article  Google Scholar  * Fisher, R. A., _The Genetical Theory of Natural Selection_ (second ed.) (Dover Publications, New York, 1958). MATH  Google Scholar  * Kempthorne, O., _An Introduction to Genetic Statistics_ (Wiley, New York, 1957). MATH  Google Scholar  * Kimura, M., _Heredity_, 12, 145 (1958). Article  Google Scholar  * Mode, C. J., _J. App. Prob._, 3, 327 (1966). Article  MathSciNet  Google Scholar  * Edwards, A. W. F., _Ann. Hum. Genet._ (submitted for publication). * Moran, P. A. P., _The Statistical Processes of Evolutionary Theory_ (Oxford Univ. Press, 1962). MATH  Google Scholar  * Scheuer, P. A. G., and Mandel, S. P. H., _Heredity_, 31, 519 (1959). Article  Google Scholar  * Mulholland, H. P., and Smith, C. A. B., _Amer. Math. Monthly_, 66, 673 (1959). Article  MathSciNet  Google Scholar  * Atkinson, F. V., Watterson, G. A., and Moran, P. A. P., _Quart. J. Math._, 11, 137 (1960). Article  ADS  Google Scholar  * Kingman, J. F. C., _Quart. J. Math._, 12, 78 (1961). Article  MathSciNet  ADS  Google Scholar  * See Li, C. C., _Population Genetics_ (Univ. Chicago Press, 1955). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Statistics, University of Aberdeen, A. W. F. EDWARDS Authors * A. W. F. EDWARDS View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE EDWARDS, A. Fundamental Theorem of Natural Selection. _Nature_ 215, 537–538 (1967). https://doi.org/10.1038/215537a0 Download citation * Received: 26 June 1967 * Published: 01 July 1967 * Issue Date: 29 July 1967 * DOI: https://doi.org/10.1038/215537a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT LI1 has pointed out, by means of a neat algebraic formulation, that Fisher's fundamental theorem of natural selection does not apply exactly in a discrete-generation


random-mating situation unless there is no dominance in fitness, and that the mean fitness cannot decrease from generation to generation for a single diallelic locus. Access through your


institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print


issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to


local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT


BEING VIEWED BY OTHERS POLYGENIC ADAPTATION: A UNIFYING FRAMEWORK TO UNDERSTAND POSITIVE SELECTION Article 29 June 2020 IDIOSYNCRATIC EPISTASIS CREATES UNIVERSALS IN MUTATIONAL EFFECTS AND


EVOLUTIONARY TRAJECTORIES Article 07 September 2020 CORRELATIONAL SELECTION IN THE AGE OF GENOMICS Article 15 April 2021 REFERENCES * Li, C. C., _Nature_, 214, 505 (1967). Article  ADS  CAS


  Google Scholar  * Fisher, R. A., _The Genetical Theory of Natural Selection_ (first ed.) (Oxford Univ. Press, 1930). Book  Google Scholar  * Fisher, R. A., _Ann. Eugen._, 11, 53 (1941).


Article  Google Scholar  * Fisher, R. A., _The Genetical Theory of Natural Selection_ (second ed.) (Dover Publications, New York, 1958). MATH  Google Scholar  * Kempthorne, O., _An


Introduction to Genetic Statistics_ (Wiley, New York, 1957). MATH  Google Scholar  * Kimura, M., _Heredity_, 12, 145 (1958). Article  Google Scholar  * Mode, C. J., _J. App. Prob._, 3, 327


(1966). Article  MathSciNet  Google Scholar  * Edwards, A. W. F., _Ann. Hum. Genet._ (submitted for publication). * Moran, P. A. P., _The Statistical Processes of Evolutionary Theory_


(Oxford Univ. Press, 1962). MATH  Google Scholar  * Scheuer, P. A. G., and Mandel, S. P. H., _Heredity_, 31, 519 (1959). Article  Google Scholar  * Mulholland, H. P., and Smith, C. A. B.,


_Amer. Math. Monthly_, 66, 673 (1959). Article  MathSciNet  Google Scholar  * Atkinson, F. V., Watterson, G. A., and Moran, P. A. P., _Quart. J. Math._, 11, 137 (1960). Article  ADS  Google


Scholar  * Kingman, J. F. C., _Quart. J. Math._, 12, 78 (1961). Article  MathSciNet  ADS  Google Scholar  * See Li, C. C., _Population Genetics_ (Univ. Chicago Press, 1955). Google Scholar 


Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Statistics, University of Aberdeen, A. W. F. EDWARDS Authors * A. W. F. EDWARDS View author publications You


can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE EDWARDS, A. Fundamental Theorem of Natural


Selection. _Nature_ 215, 537–538 (1967). https://doi.org/10.1038/215537a0 Download citation * Received: 26 June 1967 * Published: 01 July 1967 * Issue Date: 29 July 1967 * DOI:


https://doi.org/10.1038/215537a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently


available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative