Play all audios:
ABSTRACT Stopped flow and temperature jump experiments make possible a description of the individual catalytic steps. Detailed results favour the induced fit hypothesis of enzyme action.
Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this
journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now
Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer
support SIMILAR CONTENT BEING VIEWED BY OTHERS THE MEASUREMENT OF TRUE INITIAL RATES IS NOT ALWAYS ABSOLUTELY NECESSARY TO ESTIMATE ENZYME KINETIC PARAMETERS Article Open access 12 September
2023 EFFECTS OF FREEZING RATE ON STRUCTURAL CHANGES IN L-LACTATE DEHYDROGENASE DURING THE FREEZING PROCESS Article Open access 01 July 2021 DIVALENT CATIONS IN HUMAN LIVER PYRUVATE KINASE
EXEMPLIFY THE COMBINED EFFECTS OF COMPLEX-EQUILIBRIUM AND ALLOSTERIC REGULATION Article Open access 29 June 2023 REFERENCES * Schwert, G. W., Miller, B. R., and Peanasky, R. J., _J. Biol.
Chem._, 242, 3245 (1967). PubMed CAS Google Scholar * Heck, H. d'A., McMurray, C. H., and Gutfreund, H., _Biochem. J._, 108, 793 (1968). Article CAS Google Scholar * Gutfreund,
H., Cantwell, R., McMurray, C. H., Criddle, R. S., and Hathaway, G., _Biochem. J._, 106, 683 (1968). Article CAS Google Scholar * Hathaway, G., and Criddle, R. S., _Proc. US Nat. Acad.
Sci._, 56, 680 (1966). Article ADS CAS Google Scholar * Eigen, M., _Quart. Rev. Biophys._, 1, 3 (1968). Article CAS Google Scholar * Bernhard, S. A., _The Structure and Function of
Enzymes_, 248 (Benjamin, New York, 1968). Google Scholar * Monod, J., Wyman, J., and Changeux, P., _J. Mol. Biol._, 12, 88 (1965). Article CAS Google Scholar * Trentham, D. R., and
Gutfreund, H., _Biochem. J._, 106, 455 (1968). Article CAS Google Scholar * Koshland, D. E., _Proc. US Nat. Acad. Sci._, 44, 98 (1958). Article ADS CAS Google Scholar Download
references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Molecular Enzymology Laboratory, Department of Biochemistry, University of Bristol, R. S. CRIDDLE, C. H. McMURRAY & H. GUTFREUND
Authors * R. S. CRIDDLE View author publications You can also search for this author inPubMed Google Scholar * C. H. McMURRAY View author publications You can also search for this author
inPubMed Google Scholar * H. GUTFREUND View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE
CITE THIS ARTICLE CRIDDLE, R., McMURRAY, C. & GUTFREUND, H. Factors controlling the Interconversion of Enzyme–Substrate Compounds of Pig Heart Lactate Dehydrogenase. _Nature_ 220,
1091–1095 (1968). https://doi.org/10.1038/2201091a0 Download citation * Received: 09 September 1968 * Issue Date: 14 December 1968 * DOI: https://doi.org/10.1038/2201091a0 SHARE THIS ARTICLE
Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard
Provided by the Springer Nature SharedIt content-sharing initiative