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ABSTRACT STEWART _et al._1 described procedures for the preparation of rubella virus haemagglutinin in monolayers of BHK21 cells. Others expanded these studies to include extraction of
haemagglutinin with high _p_H buffers from BHK21 suspension cultures infected with rubella virus2. Production of rubella virus haemagglutinin in an established line of African green monkey
kidney cells (VERO) was recently reported3. We describe the production of haemagglutinin in the BS-C-1 line of African green monkey cells by two different strains of rubella virus and
subsequent establishment of a chronically infected culture which continues to shed virus and haemagglutinin after serial passage. SIMILAR CONTENT BEING VIEWED BY OTHERS A HAEMAGGLUTINATION
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ARTICLE PDF REFERENCES * Stewart, G. L., Parkman, P. D., Hopps, H. E., Douglas, R. D., Hamilton, J. P., and Meyer, jun., H. M., _N. Engl. J. Med._, 276, 554 (1967). Article CAS Google
Scholar * Halonen, P. E., Ryan, J. M., and Stewart, J. A., _Proc. Soc. Exp. Biol. and Med._, 125, 162 (1967). Article CAS Google Scholar * Rafajko, R. R., and zur Nedden, D. L., _Appl.
Microbiol._, 16, 803 (1968). PubMed PubMed Central CAS Google Scholar * Parkman, P. D., Buescher, E. L., and Artenstein, M. S., _Proc. Soc. Exp. Biol. and Med._, 111, 225 (1962). Article
CAS Google Scholar * Rafajko, R. R., Polakavetz, S., Handelman, B., and zur Nedden, D. L., _Appl. Microbiol._, 16, 423 (1968). PubMed PubMed Central CAS Google Scholar * Massab, H.
F., and Veronelli, J. A., _J. Bact._, 91, 436 (1966). Google Scholar * Plotkin, S. A., _Amer. J. Med. Sci._, 253, 132/356 (1967). Download references AUTHOR INFORMATION AUTHORS AND
AFFILIATIONS * Medical Research Consultants, 12601 Twinbrook Parkway, Rockville, Maryland ROBERT R. RAFAJKO & DOBOTHY ZUR NEDDEN Authors * ROBERT R. RAFAJKO View author publications You
can also search for this author inPubMed Google Scholar * DOBOTHY ZUR NEDDEN View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS
Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE RAFAJKO, R., ZUR NEDDEN, D. Rubella Haemagglutinin prepared in BS-C-1 Cells. _Nature_ 220, 1347–1349 (1968).
https://doi.org/10.1038/2201347a0 Download citation * Received: 07 October 1968 * Issue Date: 28 December 1968 * DOI: https://doi.org/10.1038/2201347a0 SHARE THIS ARTICLE Anyone you share
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