An unusual presentation of a case of t cell angiotropic (intravascular) lymphoma

An unusual presentation of a case of t cell angiotropic (intravascular) lymphoma

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Access through your institution Buy or subscribe Angiotropic lymphoma, also referred to as intravascular malignant lymphoma (IVL), is a rare non-Hodgkin's lymphoma characterized by


massive proliferation of neoplastic mononuclear cells within the lumina of venules, arterioles and capillaries.1 This entity was firstly described by Pfleger and Tappeiner in 1959 as an


endothelial neoplasm.2 Recent studies, however, unequivocally established the lymphoid nature of this rare intravascular lymphoma, based on immunohistochemical, ultrastructural and genetic


evidences.3 No atypical cells can be recognized on peripheral blood smear, since the cells reside on the lumina of the vessels. The obstruction of small blood vessels by lymphoma cells is


responsible for the clinical multiorgan ischemic manifestations. Neurological (multifocal cerebrovascular disease) and cutaneous manifestations are the most common reported,3 but also lungs,


heart, kidneys and genital female and male tracts are organs involved. We detail the first description of a case of IVL in a young adult with a clinical presentation of adult onset


Still's disease (AOSD). This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print


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local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Molina


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Google Scholar  Download references ACKNOWLEDGEMENTS This work is partially supported by grants from MURST, Associazione Italiana Ricerca Cancro (AIRC) and Fondazione M Tettamanti (AB). We


thank Mrs Cinzia Guardamagna and Ornella Micheloni for their skillful technical support. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Anatomia ed Istologia Patologica e Citodiagnostica,


Monza, Italy G Isimbaldi & MG Valente * Centro Ricerca, ‘M Tettamanti’, Clinica Pediatrica, Università di Milano-Bicocca, Italy L Corral, S Songia & A Biondi * Medicina III,


Ospedale, S Gerardo, Monza, Italy S De Bianchi Authors * G Isimbaldi View author publications You can also search for this author inPubMed Google Scholar * L Corral View author publications


You can also search for this author inPubMed Google Scholar * S Songia View author publications You can also search for this author inPubMed Google Scholar * MG Valente View author


publications You can also search for this author inPubMed Google Scholar * S De Bianchi View author publications You can also search for this author inPubMed Google Scholar * A Biondi View


author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Isimbaldi, G., Corral,


L., Songia, S. _et al._ An unusual presentation of a case of T cell angiotropic (intravascular) lymphoma. _Leukemia_ 14, 2321–2322 (2000). https://doi.org/10.1038/sj.leu.2401941 Download


citation * Received: 08 February 2000 * Accepted: 25 July 2000 * Published: 20 December 2000 * Issue Date: 01 December 2000 * DOI: https://doi.org/10.1038/sj.leu.2401941 SHARE THIS ARTICLE


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