ABSTRACT THE genome of eukaryotes is organised in nucleoprotein fibres formed by the interaction of the DNA with small basic proteins, the histones, and by specific interactions between

certain histones1. To gain more insight into the molecular organisation of chromosomes it is necessary to determine in detail the complexity and variability of the histones. The chromosomes

of eukaryotes contain five major types of histones. One of these, the very lysine-rich H1, consists of a small number of poly-peptides which differ slightly in primary structure and which

are present in different relative amounts in different tissues2. The other four histones, which are involved in histone–histone interactions, were considered homogeneous and invariable until

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Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS HISTONES AND HISTONE VARIANT FAMILIES IN PROKARYOTES

Article Open access 11 September 2024 MULTIFUNCTIONAL HISTONE VARIANTS IN GENOME FUNCTION Article 13 August 2024 THE ROLES OF HISTONE VARIANTS IN FINE-TUNING CHROMATIN ORGANIZATION AND

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AFFILIATIONS * The Institute for Cancer Research, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, Pennsylvania, 19111 SAMUEL G. FRANKLIN & ALFRED ZWEIDLER Authors * SAMUEL

G. FRANKLIN View author publications You can also search for this author inPubMed Google Scholar * ALFRED ZWEIDLER View author publications You can also search for this author inPubMed 

Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE FRANKLIN, S., ZWEIDLER, A. Non-allelic variants of histones 2a, 2b and 3 in mammals.

_Nature_ 266, 273–275 (1977). https://doi.org/10.1038/266273a0 Download citation * Received: 08 November 1976 * Accepted: 18 January 1977 * Published: 01 March 1977 * Issue Date: 17 March

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