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ABSTRACT The aim of the study was to investigate the safety and efficacy of apomorphine SL (apo SL) 2 and 3 mg, using a dose-optimisation regime in 110 Asian men with erectile dysfunction
(ED) during a 10-week open-label study. Based on daily diaries kept by each patient, 63% showed an improvement in their sexual life. Patient responses to the International Index for Erection
Function 15 questionnaires showed that there was an improvement in erectile function from baseline score after treatment with apo SL (from 15.9 to 20.4), and intercourse satisfaction (from
7.7 to 9.9), as well as slight improvements in orgasmic function (from 6.8 to 7.5) and total satisfaction (from 41.9 to 50.8). There was no marked improvement seen in sexual desire. In
conclusion, apo SL is safe and efficacious in the treatment of ED in this patient population, irrespective of underlying diseases and concomitant medications. Access through your institution
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Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Division of Urology, Department of Surgery, Chulalongkorn University Hospital, Bangkok, Thailand A Kongkanand, J Opanuraks
& K Tantiwongse * Phramongkutklao Hospital, Rajadevi, Bangkok, Thailand N Choeypunt * Department of Surgery, Siriraj Hospital, Faculty of Medicine Siriraj Hospital, Mahidol University,
Bangkok, Thailand A Tantiwong & T Amornvejsukit Authors * A Kongkanand View author publications You can also search for this author inPubMed Google Scholar * J Opanuraks View author
publications You can also search for this author inPubMed Google Scholar * K Tantiwongse View author publications You can also search for this author inPubMed Google Scholar * N Choeypunt
View author publications You can also search for this author inPubMed Google Scholar * A Tantiwong View author publications You can also search for this author inPubMed Google Scholar * T
Amornvejsukit View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to A Kongkanand. RIGHTS AND PERMISSIONS Reprints and
permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kongkanand, A., Opanuraks, J., Tantiwongse, K. _et al._ Evaluating dose regimens of apomorphine, an open-label study. _Int J Impot Res_ 15
(Suppl 2), S10–S12 (2003). https://doi.org/10.1038/sj.ijir.3900992 Download citation * Published: 24 June 2003 * Issue Date: 01 April 2003 * DOI: https://doi.org/10.1038/sj.ijir.3900992
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clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * apomorphine SL * efficacy * tolerability * epidemiology