Endogenous proviruses as “mementos”?

Endogenous proviruses as “mementos”?

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ABSTRACT In a recent News and Views1, J. P. Stoye discussed the potential health risks associated with the spread of endogenous proviruses from pigs and primates through the use of their organs for transplantation into humans. Although the risks to patients and the public from horizontal transmission may be as manageable as he represents, we would like to comment on his reference to the presence of vertically transmitted proviruses in the genomes of all mammals as “mementos”. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Stoye, J. P. _Nature_ 386, 126–127 (1997). Article  ADS  CAS  Google Scholar  * Kidwell, M. G., Kimura, K. & Black, D. M. _Genetics_ 86, 815–828 (1988). Google Scholar  * Engels, W. R. _Genetics_ 145, 11–15 (1997). Google Scholar  * Best, S., Le Tissier, P., Towers, G. & Stoye, J. P. _Nature_ 382, 826–829 (1996). Article  ADS  CAS  Google Scholar  * Pelisson, A._et al._ _ EMBO J._ 13, 4401–4411 (1994). Google Scholar  * Panthier, J. J., Condamine, H. & Jacob, F. _Proc. Natl Acad. Sci. USA_ 85, 1156–1160 (1988). Google Scholar  * Rowe, W. P. & Kozak, C. A. _Proc. Natl Acad. Sci. USA_ 77, 4871–4874 (1980). Google Scholar  * Jenkins, N. A. & Copeland, N. G. _Cell_ 43, 811–819 (1985). Google Scholar  * Lock, L. F., Jenkins, N. A. & Copeland, N. G. _Curr. Top. Microbiol. Immunol._ 171, 27–41 (1991). Google Scholar  * Lock, L. F._et al._ _ EMBO J._ 7, 4169–4177 (1988). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Center for Population Biology, University of California, Davis, 95616, California, USA Charles H. Langley * Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT, Edinburgh, UK Brian Charlesworth Authors * Charles H. Langley View author publications You can also search for this author inPubMed Google Scholar * Brian Charlesworth View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Langley, C., Charlesworth, B. Endogenous proviruses as “mementos”?. _Nature_ 388, 840 (1997). https://doi.org/10.1038/42170 Download citation * Issue Date: 28 August 1997 * DOI: https://doi.org/10.1038/42170 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT In a recent News and Views1, J. P. Stoye discussed the potential health risks associated with the spread of endogenous proviruses from pigs and primates through the use of their


organs for transplantation into humans. Although the risks to patients and the public from horizontal transmission may be as manageable as he represents, we would like to comment on his


reference to the presence of vertically transmitted proviruses in the genomes of all mammals as “mementos”. Access through your institution Buy or subscribe This is a preview of subscription


content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue


Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL


ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Stoye, J. P. _Nature_ 386, 126–127 (1997). Article  ADS  CAS 


Google Scholar  * Kidwell, M. G., Kimura, K. & Black, D. M. _Genetics_ 86, 815–828 (1988). Google Scholar  * Engels, W. R. _Genetics_ 145, 11–15 (1997). Google Scholar  * Best, S., Le


Tissier, P., Towers, G. & Stoye, J. P. _Nature_ 382, 826–829 (1996). Article  ADS  CAS  Google Scholar  * Pelisson, A._et al._ _ EMBO J._ 13, 4401–4411 (1994). Google Scholar  *


Panthier, J. J., Condamine, H. & Jacob, F. _Proc. Natl Acad. Sci. USA_ 85, 1156–1160 (1988). Google Scholar  * Rowe, W. P. & Kozak, C. A. _Proc. Natl Acad. Sci. USA_ 77, 4871–4874


(1980). Google Scholar  * Jenkins, N. A. & Copeland, N. G. _Cell_ 43, 811–819 (1985). Google Scholar  * Lock, L. F., Jenkins, N. A. & Copeland, N. G. _Curr. Top. Microbiol. Immunol._


171, 27–41 (1991). Google Scholar  * Lock, L. F._et al._ _ EMBO J._ 7, 4169–4177 (1988). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Center for


Population Biology, University of California, Davis, 95616, California, USA Charles H. Langley * Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT,


Edinburgh, UK Brian Charlesworth Authors * Charles H. Langley View author publications You can also search for this author inPubMed Google Scholar * Brian Charlesworth View author


publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Langley, C., Charlesworth, B.


Endogenous proviruses as “mementos”?. _Nature_ 388, 840 (1997). https://doi.org/10.1038/42170 Download citation * Issue Date: 28 August 1997 * DOI: https://doi.org/10.1038/42170 SHARE THIS


ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard


Provided by the Springer Nature SharedIt content-sharing initiative