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ABSTRACT The frequency of sister chromatid exchange (SCE) was measured in peripheral blood lymphocytes from control, healthy subjects and immunosuppressed recipients of cadaveric donor
kidneys with and without skin cancer. The mean SCE frequency in 43 control subjects was 9.2 per cell (range 5.4-12.3). In 30 transplant recipients with no history or evidence of cancer the
mean SCE rate was 10.3 per cell (range 5.8-24.5); four (13%) of these patients had a mean SCE frequency outside the control range. In 7 transplant recipients with skin cancer, the mean SCE
frequency was 14.3 per cell (range 9.1-19.9). This was significantly (P less than 0.01) higher than the mean value of control subjects. The mean SCE frequencies in 3 of these 7 patients fell
within the control range and in 4 of these patients was above the control range. These results suggest that some immunosuppressed kidney transplant recipients are liable to chromosomal
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WITH AGGRESSIVE NK-CELL LEUKEMIA Article 10 August 2020 Authors * G E Kelly View author publications You can also search for this author inPubMed Google Scholar * A G Sheil View author
publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Kelly, G., Sheil, A. Sister
chromatid exchange in lymphocytes from renal transplant recipients with and without cancer. _Br J Cancer_ 48, 797–801 (1983). https://doi.org/10.1038/bjc.1983.269 Download citation * Issue
Date: December 1983 * DOI: https://doi.org/10.1038/bjc.1983.269 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a
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