Access through your institution Buy or subscribe AML with t(6;11)(q27;q23) is the most prognostically unfavorable subset of AML with 11q23 abnormalities,1 with an estimated 2-year survival

of 13%2 and a median overall survival (OS) period of 12 months.3 There have been no previous reports regarding the efficacy of allogeneic hematopoietic SCT (Allo-HSCT) in adult AML with

t(6;11)(q27;q23) in the first CR. In this study, we performed a retrospective analysis of data from nine adult AML patients with t(6;11)(q27;q23) aged <60 years in the first CR to clarify

the effects of Allo-HSCT in adult AML with this chromosomal abnormality in the first CR. Data from nine adult (⩾17 years old) AML patients with t(6;11)(q27;q23) aged <60 years, diagnosed

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support REFERENCES * Mrozek K, Bloomfield CD . _Chromosome Aberrations, Gene Mutations and Expression Changes, and Prognosis in Adult Acute Myeloid Leukemia. Hematology 2006 Education

program book_. American Society of Hematology: Washington, DC, 2006, pp 169–177. Google Scholar  * Blum W, Mrózek K, Ruppert AS, Carroll AJ, Rao KW, Pettenati MJ _et al_. Adult _de novo_

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Martineau M, Berger R, Lillington DM, Moorman AV, Secker-Walker LM . The t(6;11)(q27;q23) translocation in acute leukemia: a laboratory and clinical study of 30 cases. _Leukemia_ 1998; 12:

788–791. Article  CAS  PubMed  Google Scholar  * Tamai H, Yamaguchi H, Hamaguchi H, Yagasaki H, Bessyo M, Kobayashi T _et al_. Clinical analysis of adult acute leukemia with 11q23

abnormalities: multicenter co-operative study in Japan. _Int J Hematol_ 2008; 87: 195–202. Article  PubMed  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS *

Department of Hematology, Nippon Medical School, Tokyo, Japan H Tamai, H Yamaguchi, K Tajika, K Inokuchi & K Dan * Department of Hematology, The Institute of Medical Science, The

University of Tokyo, Tokyo, Japan S Takahashi & A Tojo * Department of Hematology, Musashino Red Cross Hospital, Tokyo, Japan H Hamaguchi * Department of Hematology, Tokyo Metropolitan

Komagome Hospital, Tokyo, Japan T Kobayashi, H Akiyama & H Sakamaki * Department of Hematology, Kanazawa University, Ishikawa, Japan H Okumura & Si Nakao * Department of Hematology,

Tokyo Medical and Dental University, Tokyo, Japan A Arai & O Miura Authors * H Tamai View author publications You can also search for this author inPubMed Google Scholar * H Yamaguchi

View author publications You can also search for this author inPubMed Google Scholar * S Takahashi View author publications You can also search for this author inPubMed Google Scholar * A

Tojo View author publications You can also search for this author inPubMed Google Scholar * H Hamaguchi View author publications You can also search for this author inPubMed Google Scholar *

T Kobayashi View author publications You can also search for this author inPubMed Google Scholar * H Akiyama View author publications You can also search for this author inPubMed Google

Scholar * H Sakamaki View author publications You can also search for this author inPubMed Google Scholar * H Okumura View author publications You can also search for this author inPubMed 

Google Scholar * Si Nakao View author publications You can also search for this author inPubMed Google Scholar * A Arai View author publications You can also search for this author inPubMed 

Google Scholar * O Miura View author publications You can also search for this author inPubMed Google Scholar * K Tajika View author publications You can also search for this author inPubMed

 Google Scholar * K Inokuchi View author publications You can also search for this author inPubMed Google Scholar * K Dan View author publications You can also search for this author

inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to H Tamai. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tamai, H., Yamaguchi, H.,

Takahashi, S. _et al._ Treatment of adult AML with t(6;11)(q27;q23) by allogeneic hematopoietic SCT in the first CR. _Bone Marrow Transplant_ 42, 553–554 (2008).

https://doi.org/10.1038/bmt.2008.200 Download citation * Published: 14 July 2008 * Issue Date: October 2008 * DOI: https://doi.org/10.1038/bmt.2008.200 SHARE THIS ARTICLE Anyone you share

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