‘pangenome’ aims to capture the breadth of human diversity

‘pangenome’ aims to capture the breadth of human diversity

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LISTEN TO THE LATEST SCIENCE NEWS, WITH NICK PETRIĆ HOWE AND SHAMINI BUNDELL. Your browser does not support the audio element. Download MP3 See transcript In this episode: 00:45 MAKING A


MORE DIVERSE HUMAN GENOME The first draft of the human genome ushered in a new era of genetics research. Since its publication, researchers have constructed ever more accurate ‘reference


genomes’ – baselines against which others are compared. But these are based on the DNA of a small number of people, and don’t represent the genetic variation known to exist across human


populations. To address this, a consortium of researchers have published the first draft of a ‘pangenome’, which combines the genomes of 47 genetically diverse individuals. This draft


provides a more complete picture of the human genome, and is the starting point for a project that aims to include sequences from 350 individuals. _Research article: __Liao et al. _


_Research article: __Vollger et al._ _Research article: __Guarracino et al._ _News and Views Forum: __Human pangenome supports analysis of complex genomic regions_ 08:33 RESEARCH HIGHLIGHTS


A wearable sensor that lets users see infrared light, and how a vulture’s culture can influence its dining habits. _Research Highlight: __Wearable sensor gives a glimpse of ‘invisible’


light_ _Research Highlight: __What drives a scavenger’s diet? Vulture culture_ 11:06 BRIEFING CHAT We discuss some highlights from the Nature Briefing. This time, a new phosphate-storing


organelle found in fruit fly cells, and how extracted DNA revealed who held a deer-tooth pendant 20,000 years ago. _Nature News: __New cellular ‘organelle’ discovered inside fruit-fly


intestines_ _Nature News: __Prehistoric pendant’s DNA reveals the person who held it_ _SUBSCRIBE TO NATURE BRIEFING, AN UNMISSABLE DAILY ROUND-UP OF SCIENCE NEWS, OPINION AND ANALYSIS FREE


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