Incidence of colourblindness among four endogamous nomadic groups: an example of natural selection

Incidence of colourblindness among four endogamous nomadic groups: an example of natural selection

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SUMMARY Incidence of colourblindness among 1501 (945 males and 656 females) persons belonging to four nomadic Mendelian isolates, the Nandiwallas of Maharashtra, India, has been reported. Out of the four groups, three lacked the gene for colourblindness, while in one group the incidence was rather low (0·3 per cent). Our findings support the differential selection hypothesis for this loci of Post (1962) and Pickford (1963). 110 families with 334 children were examined for the inheritance of this trait. All matings except one were of the type normal × normal and produced all normal children; the one family of the type father colourblind × normal mother, also had all the six children with normal colour vision. The implications of the loss of the colourblind gene has been discussed in the light of nomadic way of the Nandiwallas, and also of their small effective population sizes. SIMILAR CONTENT BEING VIEWED BY OTHERS A LARGE AND DIVERSE AUTOSOMAL HAPLOTYPE IS ASSOCIATED WITH SEX-LINKED COLOUR POLYMORPHISM IN THE GUPPY Article Open access 09 March 2022 DECIPHERING THE GENETIC STRUCTURE OF THE QUEBEC FOUNDER POPULATION USING GENEALOGIES Article Open access 04 April 2023 THE DISTINCTIVE GEOGRAPHIC PATTERNS OF COMMON PIGMENTATION VARIANTS AT THE _OCA2_ GENE Article Open access 22 September 2020 ARTICLE PDF REFERENCES * Dutta, P C. 1966. A review of the inherited defective colour vision variability and selection relaxation among Indians. _Acta Genet, Basel_, 16, 327–339. CAS  PubMed  Google Scholar  * Hakim, S M. 1971. Blood and serum groups and other genetical characters of some endogamous muslim groups. Unpublished Ph.D. thesis, Bombay University. * Ishihara, S. 1968. _Tests for Colour-blindness_:Kanehara Shuppan Co., Ltd., Tokyo, Japan. Google Scholar  * Malhotra, K C. 1967. The incidence of inherited defects of colour-vision in eight endo-gamous groups of Maharashtrian Brahmins. _A Ge Me Ge_ (Rome), 16, 417–421. CAS  Google Scholar  * Malhotra, K C. 1972. Nandiwallas: Preliminary observations on a nomadic caste in Maharashtra. _Indian Statistical Institute, Technical Report series_, No. _14/72_, 1–27. * Malhotra, K C. 1973a. Pattern of nomadism. An example of social control mechanism and ecological pressures. (In Press.) * Malhotra, K C. 1973b. Incidence and inheritance of ear lobe attachment among 4 nomadic groups. _Am J Phys Anthrop_. (In Press.) * Malhotra, K G. Rate, S L, and Mutalik, G S. 1973. The genetic composition and structure of a nomadic caste-cluster in Maharashtra. (In Press.) * Malhotra, K C. Bhanu, B V. Fulmali, P M. Mutalik, G S, and Kate, S L. 1974. Finger dermatoglyphics among 4 Mendelian Isolates—an example of genetic drift-and founder effect. _Proc 1st Ann Conf Ind Soc Human Genet_, 12. (Abstract.) * Pigkford, R W. 1963. Natural selection and colourblindness. _The Eugenics Review_, 55, 97–101. Google Scholar  * Post, R H. 1962. Population differences in red and green colour vision deficiency: Review and a query on selection relaxation. _Eugenics Quarterly_, 9, 131–146. Article  CAS  Google Scholar  * Salzano, F M, and Freire-Maia, N. 1970. _Problems in Human Biology_. Wayne State University Press, Detroit. Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Indian Statistical Institute, Calcutta, c/o Deccan College, Poona, 6, India K C Malhotra * B.J. Medical College, Poona G S Mutalik & S L Kate * Deccan College, Poona, 6 B V Bhanu & P M Fulmali Authors * K C Malhotra View author publications You can also search for this author inPubMed Google Scholar * G S Mutalik View author publications You can also search for this author inPubMed Google Scholar * B V Bhanu View author publications You can also search for this author inPubMed Google Scholar * S L Kate View author publications You can also search for this author inPubMed Google Scholar * P M Fulmali View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Malhotra, K., Mutalik, G., Bhanu, B. _et al._ Incidence of colourblindness among four endogamous nomadic groups: an example of natural selection. _Heredity_ 32, 145–149 (1974). https://doi.org/10.1038/hdy.1974.17 Download citation * Received: 02 March 1973 * Issue Date: 01 April 1974 * DOI: https://doi.org/10.1038/hdy.1974.17 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

SUMMARY Incidence of colourblindness among 1501 (945 males and 656 females) persons belonging to four nomadic Mendelian isolates, the Nandiwallas of Maharashtra, India, has been reported.


Out of the four groups, three lacked the gene for colourblindness, while in one group the incidence was rather low (0·3 per cent). Our findings support the differential selection hypothesis


for this loci of Post (1962) and Pickford (1963). 110 families with 334 children were examined for the inheritance of this trait. All matings except one were of the type normal × normal and


produced all normal children; the one family of the type father colourblind × normal mother, also had all the six children with normal colour vision. The implications of the loss of the


colourblind gene has been discussed in the light of nomadic way of the Nandiwallas, and also of their small effective population sizes. SIMILAR CONTENT BEING VIEWED BY OTHERS A LARGE AND


DIVERSE AUTOSOMAL HAPLOTYPE IS ASSOCIATED WITH SEX-LINKED COLOUR POLYMORPHISM IN THE GUPPY Article Open access 09 March 2022 DECIPHERING THE GENETIC STRUCTURE OF THE QUEBEC FOUNDER


POPULATION USING GENEALOGIES Article Open access 04 April 2023 THE DISTINCTIVE GEOGRAPHIC PATTERNS OF COMMON PIGMENTATION VARIANTS AT THE _OCA2_ GENE Article Open access 22 September 2020


ARTICLE PDF REFERENCES * Dutta, P C. 1966. A review of the inherited defective colour vision variability and selection relaxation among Indians. _Acta Genet, Basel_, 16, 327–339. CAS  PubMed


  Google Scholar  * Hakim, S M. 1971. Blood and serum groups and other genetical characters of some endogamous muslim groups. Unpublished Ph.D. thesis, Bombay University. * Ishihara, S.


1968. _Tests for Colour-blindness_:Kanehara Shuppan Co., Ltd., Tokyo, Japan. Google Scholar  * Malhotra, K C. 1967. The incidence of inherited defects of colour-vision in eight endo-gamous


groups of Maharashtrian Brahmins. _A Ge Me Ge_ (Rome), 16, 417–421. CAS  Google Scholar  * Malhotra, K C. 1972. Nandiwallas: Preliminary observations on a nomadic caste in Maharashtra.


_Indian Statistical Institute, Technical Report series_, No. _14/72_, 1–27. * Malhotra, K C. 1973a. Pattern of nomadism. An example of social control mechanism and ecological pressures. (In


Press.) * Malhotra, K C. 1973b. Incidence and inheritance of ear lobe attachment among 4 nomadic groups. _Am J Phys Anthrop_. (In Press.) * Malhotra, K G. Rate, S L, and Mutalik, G S. 1973.


The genetic composition and structure of a nomadic caste-cluster in Maharashtra. (In Press.) * Malhotra, K C. Bhanu, B V. Fulmali, P M. Mutalik, G S, and Kate, S L. 1974. Finger


dermatoglyphics among 4 Mendelian Isolates—an example of genetic drift-and founder effect. _Proc 1st Ann Conf Ind Soc Human Genet_, 12. (Abstract.) * Pigkford, R W. 1963. Natural selection


and colourblindness. _The Eugenics Review_, 55, 97–101. Google Scholar  * Post, R H. 1962. Population differences in red and green colour vision deficiency: Review and a query on selection


relaxation. _Eugenics Quarterly_, 9, 131–146. Article  CAS  Google Scholar  * Salzano, F M, and Freire-Maia, N. 1970. _Problems in Human Biology_. Wayne State University Press, Detroit.


Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Indian Statistical Institute, Calcutta, c/o Deccan College, Poona, 6, India K C Malhotra * B.J. Medical


College, Poona G S Mutalik & S L Kate * Deccan College, Poona, 6 B V Bhanu & P M Fulmali Authors * K C Malhotra View author publications You can also search for this author inPubMed 


Google Scholar * G S Mutalik View author publications You can also search for this author inPubMed Google Scholar * B V Bhanu View author publications You can also search for this author


inPubMed Google Scholar * S L Kate View author publications You can also search for this author inPubMed Google Scholar * P M Fulmali View author publications You can also search for this


author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Malhotra, K., Mutalik, G., Bhanu, B. _et al._ Incidence of colourblindness


among four endogamous nomadic groups: an example of natural selection. _Heredity_ 32, 145–149 (1974). https://doi.org/10.1038/hdy.1974.17 Download citation * Received: 02 March 1973 * Issue


Date: 01 April 1974 * DOI: https://doi.org/10.1038/hdy.1974.17 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a


shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative