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SUMMARY The _a priori_ theoretical distribution of marker-linked quantitative effects in crosses involving inbred lines, and the number of quantitative loci contributing to such effects was
obtained by numerical analysis, and examined as a function of the number and effects of the quantitative loci differentiating the lines, the location of the marker relative to the chromosome
ends, and the mapping function. Over a wide range of assumptions it was found that the probability that a given marker will have an associated linked quantitative effect equal in magnitude
to 0·2 phenotypic standard deviations or greater is of the order of 0·10 or more. In most of these cases it can be expected that the marker-linked effects will be due to one, or at the most
two, quantitative loci in the vicinity of the marker. SIMILAR CONTENT BEING VIEWED BY OTHERS TEMPORAL AND GENOMIC ANALYSIS OF ADDITIVE GENETIC VARIANCE IN BREEDING PROGRAMMES Article Open
access 15 December 2021 RANK-INVARIANT ESTIMATION OF INBREEDING COEFFICIENTS Article Open access 25 November 2021 DETECTING PURGING OF INBREEDING DEPRESSION BY A SLOW RATE OF INBREEDING FOR
VARIOUS TRAITS: THE IMPACT OF ENVIRONMENTAL AND EXPERIMENTAL CONDITIONS Article 26 April 2021 ARTICLE PDF REFERENCES * Chai, C K. 1975. Genes associated with leukocyte production in mice. _J
Heredity_, 66, 301–308. Article CAS Google Scholar * Falconer, D S. 1960. _Introduction to Quantitative Genetics_. The Ronald Press Co., New York. Google Scholar * Fasoulas, A C, and
Allard, R W. 1962. Non-allelic gene interactions in the inheritance of quantitative characters in barley. _Genetics_, 47, 899–907. CAS PubMed PubMed Central Google Scholar * Law, C N.
1967. The location of genetic factors controllong a number of quantitative characters in wheat. _Genetics_, 56, 445–461. CAS PubMed PubMed Central Google Scholar * Lieberman, R, Stiffel,
C, Asofsky, R, Mouton, D, Biozzi, G, and Benaceraff, B. 1972. Genetic factors controlling anti-sheep erythrocyte antibody response and immunoglobulin synthesis in backcross and F2 progeny
of mice genetically selected for “high” or “ low ” anibody synthesis. _J Exp Med_, 136, 790–798. Article CAS PubMed PubMed Central Google Scholar * Rasmusson, J M. 1935. Studies on the
inheritance of quantitative characters in _Pisum_: I. Preliminary note on the genetics of flowering. _Hereditas_, 20, 161–180. Article Google Scholar * Sax, K. 1923. The association of
size differences with seed-coat pattern and pigmentation in _Phaseolus vulgaris_. _Genetics_, 8, 552–560. CAS PubMed PubMed Central Google Scholar * Soller, M, Genizi, A, and Brody, T.
1976. On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines. _Theoretical and Applied Genetics_, 47,
35–39. Article CAS PubMed Google Scholar * Soller, M, and Plotkin-Hazan, J. 1978. The use of marker alleles for the introgression of linked quantitative alleles. _Theoretical and Applied
Genetics_, 51, 133–137. Article Google Scholar * Stahl, F W. 1969. _The Mechanics of Inheritance_, 2nd Edition. Prentice-Hall, Inc., Englewood Cliffs, New Jersey. Google Scholar *
Strickberger, M. 1968. _Genetics_, 2nd Edition. Macmillan Co., New York. Google Scholar * Thoday, J M. 1961. Location of polygenes. _Nature_, 191, 368–370. Article Google Scholar Download
references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Genetics, The Hebrew University, Jerusalem, Israel M Soller & T Brody * Division of Statistics and Experimental
Design, Israel Agricultural Research Organisation, Bet Dagan, Israel A Genizi Authors * M Soller View author publications You can also search for this author inPubMed Google Scholar * T
Brody View author publications You can also search for this author inPubMed Google Scholar * A Genizi View author publications You can also search for this author inPubMed Google Scholar
RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Soller, M., Brody, T. & Genizi, A. The expected distribution of marker-linked quantitative effects in
crosses between inbred lines. _Heredity_ 43, 179–190 (1979). https://doi.org/10.1038/hdy.1979.73 Download citation * Received: 22 March 1979 * Issue Date: 01 October 1979 * DOI:
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