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SUMMARY Chromosome studies were carried out in 110 patients with cleft lip and/or cleft palate. Major chromosome abnormalities were found in four cases (3.6%). They included two cases of 46,
XX, 4p−, one case of 47,XY, +21 and one case of 46,XX, inv(1) (p32q12). The incidence of chromosome abnormalities in patients with cleft lip and/or cleft palate was about 5.2 times higher
than that in newborn children. SIMILAR CONTENT BEING VIEWED BY OTHERS MOLECULAR INVESTIGATION IN INDIVIDUALS WITH OROFACIAL CLEFTS AND MICROPHTHALMIA-ANOPHTHALMIA-COLOBOMA SPECTRUM Article
06 November 2023 DEEP OROFACIAL PHENOTYPING OF POPULATION-BASED INFANTS WITH ISOLATED CLEFT LIP AND ISOLATED CLEFT PALATE Article Open access 10 December 2020 GENETICS AND OROFACIAL CLEFTS:
A CLINICAL PERSPECTIVE Article Open access 23 June 2023 ARTICLE PDF REFERENCES * Akasaka, Y. 1970. Statistical and cytogenetic study on the cleft lip, alveolus and/or palate._Jap. J. Human
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177–180. CAS PubMed Google Scholar Download references AUTHOR INFORMATION Author notes * Jun-ichi Azumi & Gen-iku Kohama Present address: Department of Human Genetics, National
Institute of Genetics, Mishima, Japan AUTHORS AND AFFILIATIONS * Department of Oral Surgery, Sapporo Medical College, Sapporo, Japan Gen-iku Kohama * Department of Stomatology, Nagasaki
University School of Medicine, Nagasaki, Japan Jun-ichi Azumi & Motomasa Sasaki Authors * Jun-ichi Azumi View author publications You can also search for this author inPubMed Google
Scholar * Gen-iku Kohama View author publications You can also search for this author inPubMed Google Scholar * Motomasa Sasaki View author publications You can also search for this author
inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Azumi, Ji., Kohama, Gi. & Sasaki, M. Cytogenetic studies in patients with
cleft lip and/or cleft palate (IV). _Jap J Human Genet_ 23, 161–166 (1978). https://doi.org/10.1007/BF02001798 Download citation * Received: 25 January 1978 * Published: 01 June 1978 * Issue
Date: June 1978 * DOI: https://doi.org/10.1007/BF02001798 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a
shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * Chromosome Abnormality * Cleft
Palate * Chromosome Study * Cleave Palate * Newborn Child