ABSTRACT Blood pressure (BP) screening is important to identify those at risk of cardiovascular disease, but there has been little data on the appropriate interval of screening. We aimed to

evaluate the optimal interval and the best measure for BP re-screening by estimating the long-term, true change variance (‘signal’) and short-term, within-person variance (‘noise’). Study

design was a cohort study from 2005 to 2008. Target population was Japanese healthy adults not taking antihypertensive medication at baseline, in a teaching hospital. We measured annually

the systolic BP (SBP) and the diastolic BP (DBP), and calculated the pulse pressure (PP) and the mean arterial pressure (MAP). A total of 15 055 individuals (51% male) with a mean age of 49

optimal interval should be 3 years or more, with SBP<130 mm Hg and 2 years for those with SBP⩾130 mm Hg. Access through your institution Buy or subscribe This is a preview of subscription

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INTERNATIONAL DATABASES ON AMBULATORY AND HOME BLOOD PRESSURE IN RELATION TO CARDIOVASCULAR OUTCOME? Article Open access 03 February 2023 BLOOD PRESSURE AND ITS VARIABILITY: CLASSIC AND

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ACKNOWLEDGEMENTS We would like to thank Tomoya Okubo, Haruhiko Ohde and Asuka Nemoto for their statistical support; Sachiko Ohde, Mina Shapiro and Gautam Deshpande for their helpful

comments; Jiro Suwa and Sonoe Hiramatsu for the data collection. This work was supported in part by a UK National Institute for Health Research (NIHR) National School of Primary Care,

Department of Health grant, by a UK NIHR Health Technology Assessment (HTA) program grant, and from a grant by the Ministry of Health, Labor and Welfare in Japan for the study of the

evidence-based guideline development of screening (H19-Med-General-016) and St Luke’s Life Science Institute. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Primary Health Care,

University of Oxford, Oxford, UK O Takahashi, P P Glasziou & R Perera * Division of General Internal Medicine, Department of Medicine, St Luke's International Hospital, Tokyo,

Japan O Takahashi & T Fukui * Centre for Research in Evidence-Based Practice, Bond University, Gold Coast, Australia P P Glasziou * Department of Clinical Research and Informatics,

National Center for Global Health and Medicine, Tokyo, Japan T Shimbo Authors * O Takahashi View author publications You can also search for this author inPubMed Google Scholar * P P

Glasziou View author publications You can also search for this author inPubMed Google Scholar * R Perera View author publications You can also search for this author inPubMed Google Scholar

* T Shimbo View author publications You can also search for this author inPubMed Google Scholar * T Fukui View author publications You can also search for this author inPubMed Google Scholar

CORRESPONDING AUTHOR Correspondence to O Takahashi. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no conflict of interest. RIGHTS AND PERMISSIONS Reprints and permissions

ABOUT THIS ARTICLE CITE THIS ARTICLE Takahashi, O., Glasziou, P., Perera, R. _et al._ Blood pressure re-screening for healthy adults: what is the best measure and interval?. _J Hum

Hypertens_ 26, 540–546 (2012). https://doi.org/10.1038/jhh.2011.72 Download citation * Received: 07 April 2011 * Revised: 03 June 2011 * Accepted: 27 June 2011 * Published: 04 August 2011 *

Issue Date: September 2012 * DOI: https://doi.org/10.1038/jhh.2011.72 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry,

a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * blood pressure * mass

screening * primary prevention * cardiovascular disease * diagnostic tests