Ovarian epithelium regeneration by lgr5+ cells

Ovarian epithelium regeneration by lgr5+ cells

Play all audios:

Loading...

_Lgr5_, a marker of stem cells in many organs, is found expressed in cells scattered through the ovarian epithelium that expand to repair and regenerate the damaged ovarian surface after


each ovulation. _Lgr5_-positive stem cells in the ovary and the fimbria of the oviduct may be critical cells of origin for ovarian cancer. Access through your institution Buy or subscribe


This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access


$209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are


calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Ng, A. et al. _Nat. Cell


Biol._ 16, 745–757 (2014). Article  CAS  PubMed  Google Scholar  * Zheng, W. et al. _Hum. Mol. Genet._ 23, 920–928 (2014). Article  CAS  PubMed  Google Scholar  * Mork, L. et al. _Biol.


Reprod._ 86, 37 (2012). Article  PubMed  Google Scholar  * Szotek, P. P. et al. _Proc. Natl Acad. Sci. USA_ 105, 12469–12473 (2008). Article  CAS  PubMed  PubMed Central  Google Scholar  *


Flesken-Nikitin, A. et al. _Nature_ 495, 241–245 (2013). Article  CAS  PubMed  PubMed Central  Google Scholar  * Gamwell, L. F., Collins, O. & Vanderhyden, B. C. _Biol. Reprod._ 87, 80


(2012). Article  PubMed  Google Scholar  * Minkina, A. et al. _Dev. Cell_ 29, 511–520 (2014). Article  CAS  PubMed  PubMed Central  Google Scholar  * Parma, P. et al. _Nat. Genet._ 38,


1304–1309 (2006). Article  CAS  PubMed  Google Scholar  * Maatouk, D. M. et al. _Dev. Biol._ 383, 295–306 (2013). Article  CAS  PubMed  PubMed Central  Google Scholar  * Kim, Y. et al. _PLoS


Biol._ 4, e187 (2006). Article  PubMed  PubMed Central  Google Scholar  * Usongo, M. & Farookhi, R. _BMC Dev. Biol._ 12, 17 (2012). Article  CAS  PubMed  PubMed Central  Google Scholar


  * Paik, D. Y. et al. _Stem Cells_ 30, 2487–2497 (2012). Article  CAS  PubMed  PubMed Central  Google Scholar  * Wang, Y. et al. _PLoS ONE_ 7, e40691 (2012). Article  CAS  PubMed  PubMed


Central  Google Scholar  * Kim, J. et al. _Proc. Natl Acad. Sci. USA_ 109, 3921–3929 (2012). Article  CAS  PubMed  PubMed Central  Google Scholar  * Auersperg, N. _Front. Biosci. (Schol.


Ed.)_ 5, 709–719 (2013). Article  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Cell Biology, Duke University Medical Center, Durham, 27710,


North Carolina, USA Blanche Capel Authors * Blanche Capel View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Blanche


Capel. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE


Capel, B. Ovarian epithelium regeneration by Lgr5+ cells. _Nat Cell Biol_ 16, 743–744 (2014). https://doi.org/10.1038/ncb3020 Download citation * Published: 01 August 2014 * Issue Date:


August 2014 * DOI: https://doi.org/10.1038/ncb3020 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link


is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative