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Mitotic chromosome condensation has fascinated biologists since Flemming's early illustrations of mitosis in the late nineteenth century. Now — 130 years later — chromatid condensation
is reconstituted _in vitro_ with the minimum components. The results are remarkably and beautifully simple, requiring only core histones, three histone chaperones, topoisomerase II and
condensin I. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe
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customer support REFERENCES * Hirano, T. & Mitchison, T. J. _Cell_ 79, 449–458 (1994). Article CAS PubMed Google Scholar * Saitoh, N. et al. _J. Cell Biol._ 127, 303–318 (1994).
Article CAS PubMed Google Scholar * Saka, Y. et al., _EMBO J._ 13, 4938–4952 (1994). Article CAS PubMed PubMed Central Google Scholar * Strunnikov, A. V., Hogan, E. & Koshland,
D. _Genes Dev._ 9, 587–599 (1995). Article CAS PubMed Google Scholar * Hirano, T. & Mitchison, T. J. _J. Cell Biol._ 120, 601–612 (1993). Article CAS PubMed Google Scholar *
Hirano, T. _Nat. Rev. Mol. Cell Biol._ 7, 311–322 (2006). Article CAS PubMed Google Scholar * MacCallum, D. E. et al. _Mol. Biol. Cell_ 13, 25–39 (2002). Article CAS PubMed PubMed
Central Google Scholar * Wang, B. D. et al. _Mol. Cell Biol._ 25, 7216–7225 (2005). Article CAS PubMed PubMed Central Google Scholar * Ono, T. et al. _Mol. Biol. Cell_ 15, 3296–3308
(2004). Article CAS PubMed PubMed Central Google Scholar * Hirano, T. _Curr. Biol._ 15, R265–R275 (2005). Article CAS PubMed Google Scholar * Shintomi, K., Takahashi, T. S. &
Hirano, T. _Nat. Cell Biol._ 17, 1014–1023 (2015). Article CAS PubMed Google Scholar * Luger, K. et al. _Nature_ 389, 251–260 (1997). Article CAS PubMed Google Scholar * Philpott, A.
& Leno, G. H. _Cell_ 69, 759–67 (1992). Article CAS PubMed Google Scholar * Akey, C. W. & Luger, K. _Curr. Opin. Struct. Biol._ 13, 6–14 (2003). Article CAS PubMed Google
Scholar * Kimura, K. et al. _Science_ 282, 487–490 (1998). Article CAS PubMed Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of
Biochemistry, 279 Campus Drive, Beckman Center B-409, Stanford, 94305-5307, California, USA Jason C. Bell & Aaron F. Straight Authors * Jason C. Bell View author publications You can
also search for this author inPubMed Google Scholar * Aaron F. Straight View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR
Correspondence to Aaron F. Straight. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS
ARTICLE CITE THIS ARTICLE Bell, J., Straight, A. Condensing chromosome condensation. _Nat Cell Biol_ 17, 964–965 (2015). https://doi.org/10.1038/ncb3212 Download citation * Published: 31
July 2015 * Issue Date: August 2015 * DOI: https://doi.org/10.1038/ncb3212 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link
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