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Access through your institution Buy or subscribe Zacho J _ et al_. (2008) Genetically elevated C-reactive protein and ischemic vascular disease. _N Engl J Med_ 359: 1897–1908 Elevated levels
of C-reactive protein (CRP) are associated with an increased risk of ischemic vascular disease, but whether this association is causal has not been determined. Study of genetic variants
provides a relatively unbiased analysis of association, because gene assortment occurs randomly. Thus, Zacho _ et al_. examined whether genetic variants that elevate levels of CRP throughout
life increase the risk of ischemic cerebrovascular disease and ischemic heart disease. The analysis involved four large, independent cohorts, and included >50,000 Danish people in total.
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permissions ABOUT THIS ARTICLE CITE THIS ARTICLE High levels of C-reactive protein do not increase the risk of ischemic vascular disease. _Nat Rev Endocrinol_ 5, 64 (2009).
https://doi.org/10.1038/ncpendmet1029 Download citation * Issue Date: February 2009 * DOI: https://doi.org/10.1038/ncpendmet1029 SHARE THIS ARTICLE Anyone you share the following link with
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