Suehara Y et al. (2008) Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics. Clin Cancer Res 14: 1707–1717

The molecular background of gastrointestinal stromal tumors (GISTs) has been investigated through genome and transcriptome studies, but the proteomic profile of these tumors has not yet been

established. Suehara et al. conducted a quantitative expression study of intact proteins in GIST samples to investigate this profile and determined that decreased expression of pfetin

predicts poor outcome in patients with these tumors.