Antiangiogenic therapy in renal cell carcinoma: from concept to reality

Antiangiogenic therapy in renal cell carcinoma: from concept to reality

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Access through your institution Buy or subscribe boxed-textMotzer RJ _ et al_. (2006) Sunitinib in patients with metastatic renal cell carcinoma. _JAMA_ 295: 2516–2524 BACKGROUND This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Ratain MJ _ et al_. (2006) Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. _J Clin Oncol_ 24: 2505–2512 Article  CAS  Google Scholar  * Yang JC _ et al_. (2003) A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. _N Engl J Med_ 349: 427–434 Article  CAS  Google Scholar  * Motzer RJ _ et al_. (2006) Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. _J Clin Oncol_ 24: 16–24 Article  CAS  Google Scholar  * Motzer RJ _ et al_. (2006) Phase 3 randomized trial of sunitinib malate (SU11248) versus interferon-alfa as first-line systemic therapy for patients with metastatic renal cell carcinoma [abstract #LBA3]. _Proc Am Soc Clin Oncol_ 24: s2 Article  Google Scholar  Download references ACKNOWLEDGEMENTS The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * R Srinivasan is a Staff Clinician and WM Linehan is the Branch Chief at the Urologic Oncology Branch of the Center for Cancer Research at the National Cancer Institute, Bethesda, MD, USA., Ramaprasad Srinivasan & W Marston Linehan Authors * Ramaprasad Srinivasan View author publications You can also search for this author inPubMed Google Scholar * W Marston Linehan View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to W Marston Linehan. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Srinivasan, R., Linehan, W. Antiangiogenic therapy in renal cell carcinoma: from concept to reality. _Nat Rev Urol_ 4, 74–75 (2007). https://doi.org/10.1038/ncpuro0705 Download citation * Received: 17 November 2006 * Accepted: 20 November 2006 * Issue Date: February 2007 * DOI: https://doi.org/10.1038/ncpuro0705 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

Access through your institution Buy or subscribe boxed-textMotzer RJ _ et al_. (2006) Sunitinib in patients with metastatic renal cell carcinoma. _JAMA_ 295: 2516–2524 BACKGROUND This is a


preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per


year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated


during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Ratain MJ _ et al_. (2006) Phase II


placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinoma. _J Clin Oncol_ 24: 2505–2512 Article  CAS  Google Scholar  * Yang JC _ et


al_. (2003) A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. _N Engl J Med_ 349: 427–434 Article  CAS  Google Scholar  *


Motzer RJ _ et al_. (2006) Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with


metastatic renal cell carcinoma. _J Clin Oncol_ 24: 16–24 Article  CAS  Google Scholar  * Motzer RJ _ et al_. (2006) Phase 3 randomized trial of sunitinib malate (SU11248) versus


interferon-alfa as first-line systemic therapy for patients with metastatic renal cell carcinoma [abstract #LBA3]. _Proc Am Soc Clin Oncol_ 24: s2 Article  Google Scholar  Download


references ACKNOWLEDGEMENTS The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * R Srinivasan is a Staff


Clinician and WM Linehan is the Branch Chief at the Urologic Oncology Branch of the Center for Cancer Research at the National Cancer Institute, Bethesda, MD, USA., Ramaprasad Srinivasan 


& W Marston Linehan Authors * Ramaprasad Srinivasan View author publications You can also search for this author inPubMed Google Scholar * W Marston Linehan View author publications You


can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to W Marston Linehan. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing


financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Srinivasan, R., Linehan, W. Antiangiogenic therapy in renal cell carcinoma: from


concept to reality. _Nat Rev Urol_ 4, 74–75 (2007). https://doi.org/10.1038/ncpuro0705 Download citation * Received: 17 November 2006 * Accepted: 20 November 2006 * Issue Date: February 2007


* DOI: https://doi.org/10.1038/ncpuro0705 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not


currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative