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Mutations in hemojuvelin disrupt its ability to stimulate expression of the iron regulatory peptide hepcidin and result in the severe iron loading disorder juvenile hemochromatosis. A new
study shows that hemojuvelin acts through the multifunctional bone morphogenetic protein pathway to modulate hepcidin levels, providing new insights into communication within a key
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Contact customer support REFERENCES * Camaschella, C. _Blood_ 106, 3710–3717 (2005). Article CAS Google Scholar * Ganz, T. & Nemeth, E. _Am. J. Physiol. Gastrointest. Liver Physiol._
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AFFILIATIONS * Iron Metabolism Laboratory, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, 4029, Queensland, Australia Gregory J Anderson & David M Frazer
Authors * Gregory J Anderson View author publications You can also search for this author inPubMed Google Scholar * David M Frazer View author publications You can also search for this
author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Anderson, G., Frazer, D. Iron metabolism meets signal transduction. _Nat
Genet_ 38, 503–504 (2006). https://doi.org/10.1038/ng0506-503 Download citation * Issue Date: 01 May 2006 * DOI: https://doi.org/10.1038/ng0506-503 SHARE THIS ARTICLE Anyone you share the
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