Follicular helper T cells (TFH cells) sequentially acquire the potential to secrete interleukin 21 (IL-21) and IL-4. The shift from secretion of IL-21 to that of IL-4 modifies the nature of

the 'help' signals delivered by TFH cells to germinal center (GC) B cells. Access through your institution Buy or subscribe This is a preview of subscription content, access via

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335–368 (2016). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Simon Bélanger is in the Division of Vaccine Discovery, La Jolla Institute, La

Jolla, California, USA., Simon Bélanger * Shane Crotty is in the Division of Vaccine Discovery, and the Department of Medicine, La Jolla Institute, La Jolla, California, USA, University of

California San Diego, La Jolla, California, USA., Shane Crotty Authors * Simon Bélanger View author publications You can also search for this author inPubMed Google Scholar * Shane Crotty

View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Shane Crotty. ETHICS DECLARATIONS COMPETING INTERESTS The authors

declare no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Bélanger, S., Crotty, S. Dances with cytokines, featuring TFH

cells, IL-21, IL-4 and B cells. _Nat Immunol_ 17, 1135–1136 (2016). https://doi.org/10.1038/ni.3561 Download citation * Published: 20 September 2016 * Issue Date: October 2016 * DOI:

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