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How the immune system responds to local infection and establishes protective immunity in susceptible tissues remains unclear. Two new studies show that local tissue-resident dendritic cells
prime cytotoxic T lymphocyte responses and that memory cytotoxic T lymphocytes remain in the tissue to provide antiviral immunity. Access through your institution Buy or subscribe This is a
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during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Divito, S., Cherpes, T.L. &
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* Lanzavecchia, A. & Sallusto, F. _Curr. Opin. Immunol._ 17, 326–332 (2005). Article CAS PubMed Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Akiko
Iwasaki is in the Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA. [email protected], Akiko Iwasaki Authors * Akiko Iwasaki View author
publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Iwasaki, A. Local advantage:
skin DCs prime; skin memory T cells protect. _Nat Immunol_ 10, 451–453 (2009). https://doi.org/10.1038/ni0509-451 Download citation * Issue Date: May 2009 * DOI:
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