Little is known about how pathogenic T cells gain access to the uninflamed brain in multiple sclerosis and experimental autoimmune encephalomyelitis. A new study reports that interleukin

17–producing T helper cells enter the uninflamed central nervous system through the choroid plexus by a CCR6-CCL20–dependent mechanism. Access through your institution Buy or subscribe This

is a preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * T CELLS: AN EMERGING CAST OF ROLES IN BIPOLAR DISORDER *

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AUTHORS AND AFFILIATIONS * Robert C. Axtell and Lawrence Steinman are in the Department of Neurological Sciences and Neurology, Stanford University, Stanford, California, USA.

[email protected], Robert C Axtell & Lawrence Steinman Authors * Robert C Axtell View author publications You can also search for this author inPubMed Google Scholar * Lawrence

Steinman View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Axtell, R.,

Steinman, L. Gaining entry to an uninflamed brain. _Nat Immunol_ 10, 453–455 (2009). https://doi.org/10.1038/ni0509-453 Download citation * Issue Date: May 2009 * DOI:

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