Bmps: actions in flesh and bone

Bmps: actions in flesh and bone

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Although originally isolated from bone, BMPs control the growth, development and repair of a wide range of different tissues. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * BONE REGENERATION BY POLYHEDRAL MICROCRYSTALS FROM SILKWORM VIRUS * Goichi Matsumoto * , Takayo Ueda *  … Hajime Mori _Scientific Reports_ Open Access 06 December 2012 ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Nusslein-Vollhard, C. & Wieschaus, E. Mutations affecting segment number and polarity in Drosophila. _Nature_ 287, 795–801 (1980). Article  Google Scholar  * Urist, M.R. Bone: Formation by autoinduction. _Science._ 150, 893–899 (1965). Article  CAS  Google Scholar  * Reddi, A.H. & Huggins, C.B. Biochemical sequences in the transformation of normal fibroblasts in adolescent rat. _Proc. Nat. Acad. Sci. USA._ 69, 1601–1605 (1972). Article  CAS  Google Scholar  * Reddi, A.H. Cell biology and biochemistry of endo-chondral bone development. _Coll. Rel. Res._ 1, 209–226 (1981). Article  CAS  Google Scholar  * Reddi, A.H. Bone: Proteins: an unconventional approach to isolation of first mammalian morphogens. _Cytokine Growth Factor Review._ 8, 11–20 (1997). Article  CAS  Google Scholar  * Dudley, A.T., Lyons, K.M. & Robertson, E.J. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. _Cenes and Development._ 9, 2795–2807 (1995). CAS  Google Scholar  * Luo, G. _et al_. BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. _Genes & Development._ 9, 2808–2820 (1995). Article  CAS  Google Scholar  * Paralkar, V.M., Weeks, B.S., Yu, Y.M., Kleinman, H.K. & Reddi, A.H. Recombinant human bone morphogenetic protein 2B (BMP-4) stimulator of PCI 2 Cell Differentiation: Potentiation and binding to type IV collagen. _J. Cell Biol._ 119, 1721–1728 (1992). Article  CAS  Google Scholar  * Savage, C., Das, P., Finelli, A.L. & Padget, R. _Caenorhabditis elegans genes Sma-2, Smo-3, and Sma-4_ define a conserved family of transforming growth factor-(pathway components. _Proc. Nat. Acad. Sd. USA_ 93, 790–794 (1996). Article  CAS  Google Scholar  * Wrana, J. & Pawson, T. Mad about SMADs. _Nature_ 388, 28–29 (1997) Article  CAS  Google Scholar  * Nakao, A. _et al_. TGF-(receptor-mediated signaling through Smad 2, Smad 3, and Smad-4. _Embo J._ (in press) * Hayashi, H. _et al_. The mad-related protein Smad-7 associates with the TGF-(receptor and functions as an antagonist of TCF-(signaling). _Cell._ 89, 1165–1173 (1997). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery University of California, Davis Sacramento, California, 95817, USA A. Hari Reddi Authors * A. Hari Reddi View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Reddi, A. BMPs: Actions in flesh and bone. _Nat Med_ 3, 837–839 (1997). https://doi.org/10.1038/nm0897-837 Download citation * Issue Date: 01 August 1997 * DOI: https://doi.org/10.1038/nm0897-837 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

Although originally isolated from bone, BMPs control the growth, development and repair of a wide range of different tissues. Access through your institution Buy or subscribe This is a


preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * BONE REGENERATION BY POLYHEDRAL MICROCRYSTALS FROM SILKWORM VIRUS *


Goichi Matsumoto * , Takayo Ueda *  … Hajime Mori _Scientific Reports_ Open Access 06 December 2012 ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print


issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to


local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES *


Nusslein-Vollhard, C. & Wieschaus, E. Mutations affecting segment number and polarity in Drosophila. _Nature_ 287, 795–801 (1980). Article  Google Scholar  * Urist, M.R. Bone: Formation


by autoinduction. _Science._ 150, 893–899 (1965). Article  CAS  Google Scholar  * Reddi, A.H. & Huggins, C.B. Biochemical sequences in the transformation of normal fibroblasts in


adolescent rat. _Proc. Nat. Acad. Sci. USA._ 69, 1601–1605 (1972). Article  CAS  Google Scholar  * Reddi, A.H. Cell biology and biochemistry of endo-chondral bone development. _Coll. Rel.


Res._ 1, 209–226 (1981). Article  CAS  Google Scholar  * Reddi, A.H. Bone: Proteins: an unconventional approach to isolation of first mammalian morphogens. _Cytokine Growth Factor Review._


8, 11–20 (1997). Article  CAS  Google Scholar  * Dudley, A.T., Lyons, K.M. & Robertson, E.J. A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and


eye. _Cenes and Development._ 9, 2795–2807 (1995). CAS  Google Scholar  * Luo, G. _et al_. BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal


patterning. _Genes & Development._ 9, 2808–2820 (1995). Article  CAS  Google Scholar  * Paralkar, V.M., Weeks, B.S., Yu, Y.M., Kleinman, H.K. & Reddi, A.H. Recombinant human bone


morphogenetic protein 2B (BMP-4) stimulator of PCI 2 Cell Differentiation: Potentiation and binding to type IV collagen. _J. Cell Biol._ 119, 1721–1728 (1992). Article  CAS  Google Scholar 


* Savage, C., Das, P., Finelli, A.L. & Padget, R. _Caenorhabditis elegans genes Sma-2, Smo-3, and Sma-4_ define a conserved family of transforming growth factor-(pathway components.


_Proc. Nat. Acad. Sd. USA_ 93, 790–794 (1996). Article  CAS  Google Scholar  * Wrana, J. & Pawson, T. Mad about SMADs. _Nature_ 388, 28–29 (1997) Article  CAS  Google Scholar  * Nakao,


A. _et al_. TGF-(receptor-mediated signaling through Smad 2, Smad 3, and Smad-4. _Embo J._ (in press) * Hayashi, H. _et al_. The mad-related protein Smad-7 associates with the TGF-(receptor


and functions as an antagonist of TCF-(signaling). _Cell._ 89, 1165–1173 (1997). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Center for


Tissue Regeneration and Repair, Department of Orthopaedic Surgery University of California, Davis Sacramento, California, 95817, USA A. Hari Reddi Authors * A. Hari Reddi View author


publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Reddi, A. BMPs: Actions in flesh


and bone. _Nat Med_ 3, 837–839 (1997). https://doi.org/10.1038/nm0897-837 Download citation * Issue Date: 01 August 1997 * DOI: https://doi.org/10.1038/nm0897-837 SHARE THIS ARTICLE Anyone


you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the


Springer Nature SharedIt content-sharing initiative