ABSTRACT Molecular detection using near-infrared light between 0.9 and 1.3 eV has important biomedical applications because of greater tissue penetration and reduced auto-fluorescent

background in thick tissue or whole-blood media. Carbon nanotubes have a tunable near-infrared emission that responds to changes in the local dielectric function but remains stable to

permanent photobleaching. In this work, we report the synthesis and successful testing of solution-phase, near-infrared sensors, with β-D-glucose sensing as a model system, using

single-walled carbon nanotubes that modulate their emission in response to the adsorption of specific biomolecules. New types of non-covalent functionalization using electron-withdrawing

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grateful for funding from the National Science Foundation (grant no. CTS-0330350), the School of Chemical Sciences at UIUC, and a grant from the Molecular Electronics group, Dupont Co. The

authors thank J. Bahr for providing the blood specimen. AUTHOR INFORMATION Author notes * Paul W. Barone and Seunghyun Baik: These authors contributed equally AUTHORS AND AFFILIATIONS *

Department of Chemical and Biomolecular Engineering, University of Illinois-Urbana/Champaign, 600 S. Mathews Avenue, Urbana, 61801, Illinois, USA Paul W. Barone, Seunghyun Baik & Michael

S. Strano * Department of Chemistry, University of Illinois-Urbana/Champaign, 505 S. Mathews Avenue, Urbana, 61801, Illinois, USA Daniel A. Heller Authors * Paul W. Barone View author

publications You can also search for this author inPubMed Google Scholar * Seunghyun Baik View author publications You can also search for this author inPubMed Google Scholar * Daniel A.

Heller View author publications You can also search for this author inPubMed Google Scholar * Michael S. Strano View author publications You can also search for this author inPubMed Google

Scholar CORRESPONDING AUTHOR Correspondence to Michael S. Strano. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing financial interests. SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION Supplementary Information, Fig S1 (PDF 1439 kb) RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Barone, P., Baik, S., Heller,

D. _et al._ Near-infrared optical sensors based on single-walled carbon nanotubes. _Nature Mater_ 4, 86–92 (2005). https://doi.org/10.1038/nmat1276 Download citation * Received: 17 May 2004

* Accepted: 28 September 2004 * Published: 12 December 2004 * Issue Date: January 2005 * DOI: https://doi.org/10.1038/nmat1276 SHARE THIS ARTICLE Anyone you share the following link with

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