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Access through your institution Buy or subscribe For over fifty years, scientists have recognized the power of immunochemical reagents as a tool for analyzing biological molecules of
interest. One investigator at the vanguard of early immunoassay development was Rosalyn Yalow, whose work with Solomon Berson led to the development of the radioimmunoassay—a powerful
diagnostic tool that helped make Yalow the second woman to receive the Nobel Prize in Medicine and the first to win the Lasker Award. As early as 1960, this assay—which can be seen as a
precursor to the modern immunoprecipitation—gave investigators the power to quantify surprisingly small amounts of such important biological molecules as insulin1 and growth hormone2. This
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during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Yalow, R.S. & Berson, S.A. _J. Clin.
Invest._ 39, 1157–1175 (1960). Article CAS Google Scholar * Utiger, R.D. et al. _J. Clin. Invest._ 41, 254–261 (1962). Article CAS Google Scholar * Kronvall, G. et al. _J. Immunol._
104, 273–278 (1970). CAS PubMed Google Scholar * Kessler, S.W. _J. Immunol._ 115, 1617–1624 (1975). CAS PubMed Google Scholar * Kessler, S.W. _Current Contents_ 13, 20 (1983). Google
Scholar * Lane, D.P. & Crawford, L.V. _Nature_ 278, 261–263 (1979). Article CAS Google Scholar * Tegtmeyer, P. et al. _J. Virol._ 16, 168–178 (1975). CAS PubMed PubMed Central
Google Scholar * Harlow, E. et al. _Mol. Cell. Biol._ 6, 1579–1589 (1986). Article CAS Google Scholar Download references Authors * Michael Eisenstein View author publications You can
also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Eisenstein, M. Bound to succeed. _Nat Methods_ 2, 474
(2005). https://doi.org/10.1038/nmeth0605-474 Download citation * Issue Date: June 2005 * DOI: https://doi.org/10.1038/nmeth0605-474 SHARE THIS ARTICLE Anyone you share the following link
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