Characteristics of SADS | Nature Reviews Cardiology

Characteristics of SADS | Nature Reviews Cardiology

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Sudden arrhythmic death syndrome (SADS) occurs more often during sleep or at rest than during exercise or emotional stress, and in some patients might be associated with epilepsy. This finding comes from a retrospective study of post-mortem examinations conducted between 1994 and 2010 at the Cardiac Risk in the Young Centre for Cardiac Pathology in London, UK. SADS is a form of sudden cardiac death in which the heart is morphologically normal, and the toxicology report is negative.During the study period, 2,156 cases of sudden cardiac death were referred to the centre for assessment. Structural heart disease or another overt cause of death was established in 1,189 patients, leaving 967 deaths (45%) attributed to SADS. Of this group, 61% were male, and

Sudden arrhythmic death syndrome (SADS) occurs more often during sleep or at rest than during exercise or emotional stress, and in some patients might be associated with epilepsy. This


finding comes from a retrospective study of post-mortem examinations conducted between 1994 and 2010 at the Cardiac Risk in the Young Centre for Cardiac Pathology in London, UK. SADS is a


form of sudden cardiac death in which the heart is morphologically normal, and the toxicology report is negative.


During the study period, 2,156 cases of sudden cardiac death were referred to the centre for assessment. Structural heart disease or another overt cause of death was established in 1,189


patients, leaving 967 deaths (45%) attributed to SADS. Of this group, 61% were male, and