Play all audios:
Access through your institution Buy or subscribe An individualized treatment regimen with high-dose cabergoline may help women with tumor-related hyperprolactinemic infertility to achieve
pregnancy, say researchers from Japan. “Our findings should be very encouraging for both patients and physicians because it became apparent that every infertile patient with prolactinoma
could conceive safely with cabergoline, independent of tumor size or drug resistance or intolerance,” declare Masami Ono and Nobuhiro Miki, two of the investigators involved in this
prospective study. Prolactinoma is the underlying cause of infertility in a high proportion of women of reproductive age; however, two important issues must be considered before fertility
treatment can be initiated in such cases. First, tumors can be resistant to first-line treatment with bromocriptine, which forces many women to abandon the idea of having children. Second,
macroprolactinomas can enlarge during pregnancy, resulting in visual problems and severe headaches. This complication is conventionally prevented by pregestational surgical debulking of the
tumor or radiation therapy before receiving medical therapy. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe
to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF
Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact
customer support ORIGINAL RESEARCH PAPER * Ono, M. _ et al_. Individualized high-dose cabergoline therapy for hyperprolactinemic infertility in women with micro- and macroprolactinomas. _J.
Clin. Endocrinol. Metab._ 95, 2672–2679 (2010) Article CAS PubMed Google Scholar Download references Authors * Vicky Heath View author publications You can also search for this author
inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Heath, V. High-dose cabergoline improves pregnancy rates in women with
prolactinomas. _Nat Rev Endocrinol_ 6, 415 (2010). https://doi.org/10.1038/nrendo.2010.95 Download citation * Issue Date: August 2010 * DOI: https://doi.org/10.1038/nrendo.2010.95 SHARE THIS
ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard
Provided by the Springer Nature SharedIt content-sharing initiative