Romosozumab, a recently developed sclerostin inhibitor, stimulates bone formation and inhibits bone resorption, thereby markedly increasing bone mass and reducing fracture risk. But will a

red flag regarding possible adverse cardiovascular events derail this promising new drug for osteoporosis? Access through your institution Buy or subscribe This is a preview of subscription

content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * CARDIOPROTECTIVE FUNCTION OF SCLEROSTIN BY REDUCING CALCIUM DEPOSITION, PROLIFERATION, AND

APOPTOSIS IN HUMAN VASCULAR SMOOTH MUSCLE CELLS * Sheila González-Salvatierra * , Cristina García-Fontana *  … Beatriz García-Fontana _Cardiovascular Diabetology_ Open Access 02 November

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author's work is supported by NIH grants AG004875, AG048792 and AR027065. In addition, the author greatly appreciates the critical review of this article by M. Drake and J. Farr.

AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Robert and Arlene Kogod Center on Aging and the Endocrine Research Unit, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, 55905,

Minnesota, USA Sundeep Khosla Authors * Sundeep Khosla View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Sundeep

Khosla. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing financial interests. POWERPOINT SLIDES POWERPOINT SLIDE FOR TABLE 1 RIGHTS AND PERMISSIONS Reprints and

permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Khosla, S. Romosozumab — on track or derailed?. _Nat Rev Endocrinol_ 13, 697–698 (2017). https://doi.org/10.1038/nrendo.2017.136 Download

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