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Serum PSA testing remains controversial as the data regarding its utility are conflicting. However, a recent study adds to the growing body of evidence supporting its usefulness in
middle-aged men, especially in the determination of the long-term risk of metastasis and death from prostate cancer. Access through your institution Buy or subscribe This is a preview of
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ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * National Cancer Institute. _Surveillance Epidemiology
and End Results_ [online]. * Nadler, R. B., Humphrey, P. A., Smith, D. S., Catalona, W. J. & Ratliff, T. L. Effect of Inflammation and Benign Prostatic Hyperplasia on Elevated Serum
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and long term risk of metastasis: case-control study. _BMJ_ 346, f2023 (2013). Article Google Scholar * Loeb, S., Carter, H. B., Catalona, W. J., Moul, J. W. & Schroder, F. H. Baseline
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concentration at age 60 and death or metastasis from prostate cancer: case-control study. _BMJ_ 341, c4521 (2010). Article Google Scholar * Grenabo Bergdahl, A., Holmberg, E., Moss, S.
& Hugosson, J. Incidence of Prostate Cancer After Termination of Screening in a Population-based Randomised Screening Trial. _Eur. Urol._ doi:10.1016/j.eururo.2013.05.024. * Scosyrev,
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E137–E138 (2012). Google Scholar Download references ACKNOWLEDGEMENTS We thank Stacy Loeb for reviewing this manuscript. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Urology,
Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 16-703, Chicago, 60611-3008, IL, USA Daniel Reinhardt & William J. Catalona Authors * Daniel
Reinhardt View author publications You can also search for this author inPubMed Google Scholar * William J. Catalona View author publications You can also search for this author inPubMed
Google Scholar CORRESPONDING AUTHOR Correspondence to William J. Catalona. ETHICS DECLARATIONS COMPETING INTERESTS W. J. Catalona declares that he has received research support and honoraria
for speaking and been an investigator for Beckman-Coulter, has received research support and royalties as co-inventor from and been an investigator and consultant for OHMX, has received
research support from and been an investigator for deCODE genetics, and has been an investigator for Nanosphere. D. Reinhardt declares no competing interests. RIGHTS AND PERMISSIONS Reprints
and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Reinhardt, D., Catalona, W. The growing evidence supporting mid-life PSA testing. _Nat Rev Urol_ 10, 436–438 (2013).
https://doi.org/10.1038/nrurol.2013.144 Download citation * Published: 02 July 2013 * Issue Date: August 2013 * DOI: https://doi.org/10.1038/nrurol.2013.144 SHARE THIS ARTICLE Anyone you
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