Access through your institution Buy or subscribe Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer, but the molecular pathogenesis of the disease

remains poorly understood. Two recently published studies have sought to remedy this situation by analysing the genetic changes underlying the disease. In a recent article in _Nature_, The

Cancer Genome Atlas Research Network report their survey of over 400 tumours to identify significantly mutated genes. Using a number of different genomic platforms—including RNA sequencing,

DNA methylation arrays, miRNA sequencing, single nucleotide polymorphism (SNP) arrays, reverse phase protein arrays and exome sequencing—the group identified 19 genes that were significantly

are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support ORIGINAL RESEARCH PAPERS * The Cancer

Genome Atlas Research Network. Comprehensive molecular characterization of clear cell renal cell carcinoma. _Nature_ doi:10.1038/nature12222 * Sato, Y. _ et al_. Integrated molecular

analysis of clear-cell renal cell carcinoma. _Nat. Genet._ doi:10.1038/ng.2699 Article  CAS  PubMed Central  Google Scholar  Download references Authors * Annette Fenner View author

publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Fenner, A. Creating a molecular

atlas of clear cell renal cell carcinoma genetics. _Nat Rev Urol_ 10, 489 (2013). https://doi.org/10.1038/nrurol.2013.151 Download citation * Published: 09 July 2013 * Issue Date: September

2013 * DOI: https://doi.org/10.1038/nrurol.2013.151 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link

is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative