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KEY POINTS * Nocturia remains underreported and undertreated, despite its prevalence and association with significant morbidity and mortality * Nocturia has multiple aetiologies, including
overproduction of urine (global polyuria and nocturnal polyuria), reduced bladder storage capacity, sleep disorders and a combination of these conditions * The frequency volume chart,
Nocturia Quality of Life questionnaire and the duration of the first uninterrupted sleep period should be used in the assessment and follow-up monitoring of each patient * Management
strategies should be targeted to each patient's specific aetiology of nocturia; some patients might require multicomponent therapies ABSTRACT Nocturia is an extremely common condition
that has major sequelae for affected patients. Through disruption of sleep, nocturia impairs quality of life and worsens health outcomes, and is associated with a variety of morbidities
including diabetes, coronary artery disease, obstructive sleep apnoea, obesity, metabolic syndrome, and depression. Unsurprisingly, several studies have also linked nocturia with reduced
survival. Nocturia is not simply a consequence of lower urinary tract disease; rather, it is a multifactorial disorder that is often a manifestation of an underlying renal or systemic
disease. Through the use of the frequency volume chart, clinicians can accurately quantify nocturia and determine its aetiology. Evaluation of quality of life and sleep using simple measures
is essential in order to assess the impact of nocturia on a patient. Numerous treatment options for nocturia exist, but most are associated with minor benefit or lack sufficient evidence
supporting their use. By systematically analysing an individual's causes of nocturia, clinicians can design appropriate treatment strategies to most effectively treat this condition.
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support SIMILAR CONTENT BEING VIEWED BY OTHERS NOCTURIA AND OBSTRUCTIVE SLEEP APNOEA Article 23 May 2024 HYPERTENSION, CARDIOVASCULAR DISEASE, AND NOCTURIA: A SYSTEMATIC REVIEW OF THE
PATHOPHYSIOLOGICAL MECHANISMS Article 03 March 2021 ASSOCIATION BETWEEN NOCTURIA AND SLEEP ISSUES, INCORPORATING THE IMPACT OF LIFESTYLE HABITS PERCEIVED AS PROMOTING SLEEP IN AN INTERNET
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18, 213–220 (2014). Article PubMed PubMed Central Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Urology, SUNY Downstate College of
Medicine, 450 Clarkson Avenue, Brooklyn, 11226, New York, USA Hasan Dani, Ashanda Esdaille & Jeffrey P. Weiss Authors * Hasan Dani View author publications You can also search for this
author inPubMed Google Scholar * Ashanda Esdaille View author publications You can also search for this author inPubMed Google Scholar * Jeffrey P. Weiss View author publications You can
also search for this author inPubMed Google Scholar CONTRIBUTIONS J.P.W. and H.D. discussed the content for this article and wrote it, H.D. researched data for this article and all authors
were involved in the review and editing of the article before submission. CORRESPONDING AUTHOR Correspondence to Jeffrey P. Weiss. ETHICS DECLARATIONS COMPETING INTERESTS J.P.W. declares
that he serves as consultant for Allergan, Astellas, Elsevier, Ferring, Pfizer, Symptelligence and Vantia. H.D. and A.E. declare no competing interests. POWERPOINT SLIDES POWERPOINT SLIDE
FOR TABLE 1 RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Dani, H., Esdaille, A. & Weiss, J. Nocturia: aetiology and treatment in adults. _Nat Rev
Urol_ 13, 573–583 (2016). https://doi.org/10.1038/nrurol.2016.134 Download citation * Published: 26 July 2016 * Issue Date: October 2016 * DOI: https://doi.org/10.1038/nrurol.2016.134 SHARE
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