Predicting 68ga-psma-pet–ct positivity for recurrent disease

Predicting 68ga-psma-pet–ct positivity for recurrent disease

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Access through your institution Buy or subscribe Using 68Ga-labelled prostate-specific membrane antigen (PSMA) ligand-positron-emission tomography (PET)–CT imaging can improve detection


rates of recurrent prostate cancer. The largest study to date, published in _European Urology_, shows that using this imaging modality to detect disease in patients with early biochemical


recurrence after radical prostatectomy could influence treatment decisions in these men. Two nomograms for predicting positive findings using this imaging modality have been developed to


help select men who might benefit from undergoing this procedure. In total, 272 patients who had hormone-sensitive biochemical recurrence of prostate cancer, had received radical


prostatectomy as their primary treatment, and had serum PSA values between 0.2 and 1.0 ng/ml at the time of imaging were included in the study. This cohort was split into two subgroups:


very-low PSA values (0.2–0.5 ng/ml) and low PSA values (>0.5–1.0 ng/ml). This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your


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REFERENCES * Rauscher, I. _ et al_. Efficacy, predictive factors, and prediction nomograms for 68Ga-labeled prostate-specific membrane antigen–ligand positron-emission tomography/computed


tomography in early biochemical recurrent prostate cancer after radical prostatectomy. _Eur. Urol._ https://doi.org/10.1016/j.eururo.2018.01.006 (2018) Article  Google Scholar  Download


references Authors * Louise Stone View author publications You can also search for this author inPubMed Google Scholar RELATED LINKS RELATED LINKS IN NATURE RESEARCH Maurer, T. _ et al_.


Current use of PSMA–PET in prostate cancer management. _Nat. Rev. Urol._ 13, 226–235 (2016) RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Stone, L.


Predicting 68Ga-PSMA-PET–CT positivity for recurrent disease. _Nat Rev Urol_ 15, 137 (2018). https://doi.org/10.1038/nrurol.2018.15 Download citation * Published: 13 February 2018 * Issue


Date: March 2018 * DOI: https://doi.org/10.1038/nrurol.2018.15 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a


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