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Recent studies suggest that the Spt16 protein of FACT shuttles H2A–H2B dimers off and on nucleosomes during transcription elongation. By restoring nucleosomes after passage of RNA polymerase
II, Spt16 and Spt6 prevent transcription from cryptic promoters in coding regions that would otherwise be expressed in the absence of histones. Access through your institution Buy or
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are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * van Holde, K.E., Lohr,
D.E. & Robert, C. _J. Biol. Chem._ 267, 2837–2840 (1992). CAS PubMed Google Scholar * Belotserkovskaya, R. et al. _Science_ 301, 1090–1093 (2003). Article CAS PubMed Google Scholar
* Kaplan, C.D., Laprade, L. & Winston, F. _Science_ 301, 1096–1099 (2003). Article CAS PubMed Google Scholar * Saunders, A. et al. _Science_ 301, 1094–1096 (2003). Article CAS
PubMed Google Scholar * Mason, P.B. & Struhl, K. _Mol. Cell. Biol._ 23, in the press (2003). * Winston, F. In _Transcriptional Regulation_ (eds. McKnight, S.L. & Yamamoto, K.R.)
1271–1293 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1992). Google Scholar * Jackson, V. _Biochemistry_ 29, 719–731 (1990). Article CAS PubMed Google Scholar *
Bortvin, A. & Winston, F. _Science_ 272, 1473–1476 (1996). Article CAS PubMed Google Scholar * Ahmad, K. & Henikoff, S. _Mol. Cell._ 9, 1191–1200 (2002). Article CAS PubMed
Google Scholar * Lindstrom, D.L. et al. _Mol. Cell. Biol._ 23, 1368–1378 (2003). Article CAS PubMed PubMed Central Google Scholar * Shimojima, T. et al. _Genes Dev._ 17, 1605–1616
(2003). Article CAS PubMed PubMed Central Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Stowers Institute for Medical Research, 1000 East 50th Street,
Kansas City, 64110, Missouri, USA Michael J Carrozza, Thomas Kusch & Jerry L Workman Authors * Michael J Carrozza View author publications You can also search for this author inPubMed
Google Scholar * Thomas Kusch View author publications You can also search for this author inPubMed Google Scholar * Jerry L Workman View author publications You can also search for this
author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Michael J Carrozza. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Carrozza, M.,
Kusch, T. & Workman, J. Repairing nucleosomes during transcription. _Nat Struct Mol Biol_ 10, 879–880 (2003). https://doi.org/10.1038/nsb1103-879 Download citation * Issue Date: 01
November 2003 * DOI: https://doi.org/10.1038/nsb1103-879 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable
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