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ABSTRACT Summary: The present stuck was carried out to assess the activities of all three principal isoenzymes of human erythrocyte carbonic anhydrase (IICA) in newborn infants in relation
to their estimated gestational ages. Blood samples were collected at parturition from the umbilical cords of 45 normal healthy infants. Among the samples taken before day 290 of gestation,
the activity ratio (isoenzyme It: isoenzyme C) was correlated significantly with estimated gestational age. After day 290, the range of B:C activity ratios was similar to that observed in
adults. Isoenzyme A represented a relatively constant proportion (mean ± SEM) at 7.2 ± 0.2% of total HCA activity. The B:C activity ratio appears to be a more reliable and sensitive index of
maturity than either the total HCA activity or the ratio of total HCA activity to the total hemoglobin concentration in cord blood. Speculation: The progressive change in the ratio of
activities of IICA isoenzymes B and C in cord blood from day 253 to day 290 of gestation is of potential utility in the accurate estimation of gestational age within the range. SIMILAR
CONTENT BEING VIEWED BY OTHERS SERUM ERYTHROFERRONE LEVELS DURING THE FIRST MONTH OF LIFE IN PREMATURE INFANTS Article 10 August 2021 SERUM FERRITIN VALUES IN NEONATES <29 WEEKS’
GESTATION ARE HIGHLY VARIABLE AND DO NOT CORRELATE WITH RETICULOCYTE HEMOGLOBIN CONTENT Article 18 August 2023 IRON HOMEOSTASIS IN FULL-TERM, NORMAL BIRTHWEIGHT GAMBIAN NEONATES OVER THE
FIRST WEEK OF LIFE Article Open access 26 June 2023 ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Physiology, University College Dublin, Dublin, Ireland J B
Moynihan Authors * J B Moynihan View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE
THIS ARTICLE Moynihan, J. Relationship between Maturity and Isoenzymes of Erythrocytic Carbonic Anhydrase in Newborn Infants. _Pediatr Res_ 11, 871–873 (1977).
https://doi.org/10.1203/00006450-197708000-00001 Download citation * Issue Date: 01 August 1977 * DOI: https://doi.org/10.1203/00006450-197708000-00001 SHARE THIS ARTICLE Anyone you share
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