472 hepatitis b during pregnancy: identification of high risk groups

472 hepatitis b during pregnancy: identification of high risk groups

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ABSTRACT Recent studies confirming the efficacy of hepatitis B immune globulin for the prevention of neonatal hepatitis B virus (HBV) infection have highlighted the need for identifying high risk pregnant women in the United States. During the period March to November 1980, of 300 pregnant women of Chinese extraction at New York Infirmary Hospital who were tested for hepatitis B surface antigen (HBsAg), 43 (14.3%) were positive. Of 37 HBsAg-positive women who were tested for ‘e’ antigen (HBeAg), 18 (48.6%) were positive. Of 236 women who were tested for both HBsAg and its antibody (anti-HBs), 132 (56%) had evidence of present or past HBV infection; 13.5% HBsAg-positive and 42.5% anti-HBs-positive. About 98% of the women were born outside the United States, 80 to 90% from Mainland China and Hong Kong and the others from Taiwan, Burma, Macau and other islands. Their length of stay in the USA ranged from 3 months to 15 years. In view of these findings Chinese women should be routinely tested for HBsAg during pregnancy. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pediatrics, New York University School of Medicine, New York Infirmary-Beekman Downtown Hospital, New York Madhu Gudavalli, Catherine M P Kierney & Saul Krugman Authors * Madhu Gudavalli View author publications You can also search for this author inPubMed Google Scholar * Catherine M P Kierney View author publications You can also search for this author inPubMed Google Scholar * Saul Krugman View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gudavalli, M., Kierney, C. & Krugman, S. 472 HEPATITIS B DURING PREGNANCY: IDENTIFICATION OF HIGH RISK GROUPS. _Pediatr Res_ 15 (Suppl 4), 519 (1981). https://doi.org/10.1203/00006450-198104001-00485 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00485 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT Recent studies confirming the efficacy of hepatitis B immune globulin for the prevention of neonatal hepatitis B virus (HBV) infection have highlighted the need for identifying high


risk pregnant women in the United States. During the period March to November 1980, of 300 pregnant women of Chinese extraction at New York Infirmary Hospital who were tested for hepatitis


B surface antigen (HBsAg), 43 (14.3%) were positive. Of 37 HBsAg-positive women who were tested for ‘e’ antigen (HBeAg), 18 (48.6%) were positive. Of 236 women who were tested for both HBsAg


and its antibody (anti-HBs), 132 (56%) had evidence of present or past HBV infection; 13.5% HBsAg-positive and 42.5% anti-HBs-positive. About 98% of the women were born outside the United


States, 80 to 90% from Mainland China and Hong Kong and the others from Taiwan, Burma, Macau and other islands. Their length of stay in the USA ranged from 3 months to 15 years. In view of


these findings Chinese women should be routinely tested for HBsAg during pregnancy. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pediatrics, New York University


School of Medicine, New York Infirmary-Beekman Downtown Hospital, New York Madhu Gudavalli, Catherine M P Kierney & Saul Krugman Authors * Madhu Gudavalli View author publications You


can also search for this author inPubMed Google Scholar * Catherine M P Kierney View author publications You can also search for this author inPubMed Google Scholar * Saul Krugman View


author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gudavalli, M., Kierney,


C. & Krugman, S. 472 HEPATITIS B DURING PREGNANCY: IDENTIFICATION OF HIGH RISK GROUPS. _Pediatr Res_ 15 (Suppl 4), 519 (1981). https://doi.org/10.1203/00006450-198104001-00485 Download


citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00485 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content:


Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative