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ABSTRACT Transpyloric (TP) feeding has been used as a method of feeding the smaller (<1200 gms) infant. We have noticed that many of our infants being fed with a “reformulated” premature
infant formula (Enfamil) by TP route have developed clotted feeding tubes in spite of regular irrigation with sterile water. During a 9 month period, we studied all infants fed either the
premature formula or their own mothers milk via TP route. An in vitro study was also conducted comparing the premature infant formula and a standard formula with human milk placed in TP
tubes at the milk's own original pH and alkaline pH.Fifty-nine infants received TP feedings; 39 were fed premature formula and 20 received human milk. Birth weight and gestational ages
between the two groups were similar. No infant receiving human milk developed a clotted feeding tube. However, 15 of the 39 (38%) infants receiving premature formula developed at least one
clotted tube. The clotted group was smaller in birth weight (mean of 1044 vs. 1418 gms, p<.001), and younger in gestational age (29 vs. 32 weeks, p<.05) than the non-clotted group.
There were no differences between the two groups in age of initial feeding or rate of infusion. The in vitro study showed that the tubes were completely occluded, consistently, after 24
hours for the premature formula at both original pH (6.70) and alkaline pH (8.0). Neither the human milk nor the standard formula developed any clot. We feel that premature infant formulas
should be used with caution when used via the transpyloric route. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pediatrics, University of Utah, Salt Lake City,
Utah. Laurie Moyer, Gary Chan & Lowell Glasgow Authors * Laurie Moyer View author publications You can also search for this author inPubMed Google Scholar * Gary Chan View author
publications You can also search for this author inPubMed Google Scholar * Lowell Glasgow View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND
PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Moyer, L., Chan, G. & Glasgow, L. 611 CLOTTED TRANSPYLORIC FEEDING TUBES USING A PREMATURE FORMULA. _Pediatr
Res_ 15 (Suppl 4), 542 (1981). https://doi.org/10.1203/00006450-198104001-00624 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00624 SHARE
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