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ABSTRACT Calcium (Ca) and phosphorus (P) deficiency was observed in earlier studies of 17 preterm infants fed a preparation of fortified mother's milk derived from pasteurized,
lyophilized fractions of mature human milk (Group I, birthweight, 1178 ± 36 g, gestation, 29 ± 0.2 wk, Mean ± SEM). A modified preparation of this fortified mother's milk with added Ca
lactate and P salts was fed to 8 infants (Group II, 1088 ± 53 g, 28 ± 0.3 wk) for the first two months postnatally. 96-h balance studies were conducted at approximately weeks 3 and 7. Group
II achieved significantly greater intakes (CaI, PI), retentions (CaR, PR), and absorptions (CaABS, PABS) of both Ca and P, and greater urinary excretion of P(PU). Proportionally greater
urinary excretion of Ca(CaU) was observed in Group I (P = 0.003). Serum P was greater and alkaline phosphatase was lower in Group II (P < 0.01). These results indicate that the addition
of both Ca and P to fortified mother's milk will reverse Ca and P insufficiency and lead to retentions of Ca and P which approach the fetal accretion more closely than previous human
milk preparations. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pediatrics, Baylor College of Medicine, USDA/ARS Children's Nutrition Research Center,
Houston, TX Richard J Schanler, Cutberto Garza & Buford L Nichols Authors * Richard J Schanler View author publications You can also search for this author inPubMed Google Scholar *
Cutberto Garza View author publications You can also search for this author inPubMed Google Scholar * Buford L Nichols View author publications You can also search for this author inPubMed
Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Schanler, R., Garza, C. & Nichols, B. 727 COMPARISON OF THE EFFICACY OF CA AND P
FORTIFICATION IN HUMAN MILK. _Pediatr Res_ 19, 232 (1985). https://doi.org/10.1203/00006450-198504000-00757 Download citation * Issue Date: 01 April 1985 * DOI:
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