ABSTRACT During the last few years there has been a rising incidence of Candida Sepsis in VLBW. The conventional treatment with Ampho and 5 Fluocytosine is associated with toxic effects.

During the years 1986-1987 nine preterms, mean birth weight 1041 ± 269 gm's, mean gestational age 28.2 ± 1.92 wks with systemic candidiasis were treated in our department. Ampho

protocol- Day I.–Test dose 0.1 mg/kg. Complementary dose up to 0.25 mg/kg. Day II:-0.5mg/kg. Day III:1.0 mg/kg. Day IV:-onwards alternate day 1 mg/kg for 4-6 wks. Diluted in 5% glucose as

0.1 mg/ml administered over 6 hrs. Monitoring of body temp. H.R., R.R., B.P., urine output and daily blood count, electrolytes. Urea and creatinine and biweekly transaminases. None of the

Center, IsraelSackler School of Medicine, Israel N Naor, A Litwin, I Litmanowitz & M Drucker Authors * N Naor View author publications You can also search for this author inPubMed Google

Scholar * A Litwin View author publications You can also search for this author inPubMed Google Scholar * I Litmanowitz View author publications You can also search for this author inPubMed

 Google Scholar * M Drucker View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS

ARTICLE Naor, N., Litwin, A., Litmanowitz, I. _et al._ Minimal toxic effects with alternate day Amphoteric in B (Ampho) treatment for candidiasis in V.L.B.W.. _Pediatr Res_ 26, 523 (1989).

https://doi.org/10.1203/00006450-198911000-00141 Download citation * Issue Date: 01 November 1989 * DOI: https://doi.org/10.1203/00006450-198911000-00141 SHARE THIS ARTICLE Anyone you share

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