91 adipose tissue fat composition measured by carbon 13 magnetic resonance spectroscopy

91 adipose tissue fat composition measured by carbon 13 magnetic resonance spectroscopy

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ABSTRACT Natural abundance carbon 13 magnetic resonance spectroscopy (13C MRS) allows the proportion of saturated and unsaturated fatty acids in adipose tissue to be measured repeatedly and non-invasively. Eleven infants and two of their mothers underwent 13C MRS. Ten infants were studied in the first week of life, one also at 6 weeks and one at 10 weeks only. Using an enveloping transmitter coil and a surface receiver coil, coupled 13C spectra were obtained with repetition times of 0.3 seconds and 30 seconds. These were analysed by the NMRI curve fitting program and the percentages of saturated and unsaturated fatty acids calculated1. The results are shown either individually or as the median and range in the table: One of the two mothers studied, a vegan, had a higher proportion of unsaturated fatty acids compared to the other mother who consumed a mixed diet (87% vs 71 %). These preliminary results suggest that 13C MRS might be used to perform longitudinal studies of different influences on the composition of adipose tissue in infants. 1 Magnetic Resonance in Medicine, 1992:27:97-106 ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * David Edwards. Department of Paediatrics and Neonatal Medicine, and the Robert Steiner MR Unit, Royal Postgraduate Medical School, London Don Hanrahan, Louise Thomas, Jimmy Bell, Denis Azzopardi, Janet Sargentoni, Maria Barnard, David Bryant & Graeme Bydder Authors * Don Hanrahan View author publications You can also search for this author inPubMed Google Scholar * Louise Thomas View author publications You can also search for this author inPubMed Google Scholar * Jimmy Bell View author publications You can also search for this author inPubMed Google Scholar * Denis Azzopardi View author publications You can also search for this author inPubMed Google Scholar * Janet Sargentoni View author publications You can also search for this author inPubMed Google Scholar * Maria Barnard View author publications You can also search for this author inPubMed Google Scholar * David Bryant View author publications You can also search for this author inPubMed Google Scholar * Graeme Bydder View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Hanrahan, D., Thomas, L., Bell, J. _et al._ 91 ADIPOSE TISSUE FAT COMPOSITION MEASURED BY CARBON 13 MAGNETIC RESONANCE SPECTROSCOPY. _Pediatr Res_ 36, 18 (1994). https://doi.org/10.1203/00006450-199407000-00091 Download citation * Issue Date: 01 July 1994 * DOI: https://doi.org/10.1203/00006450-199407000-00091 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT Natural abundance carbon 13 magnetic resonance spectroscopy (13C MRS) allows the proportion of saturated and unsaturated fatty acids in adipose tissue to be measured repeatedly and


non-invasively. Eleven infants and two of their mothers underwent 13C MRS. Ten infants were studied in the first week of life, one also at 6 weeks and one at 10 weeks only. Using an


enveloping transmitter coil and a surface receiver coil, coupled 13C spectra were obtained with repetition times of 0.3 seconds and 30 seconds. These were analysed by the NMRI curve fitting


program and the percentages of saturated and unsaturated fatty acids calculated1. The results are shown either individually or as the median and range in the table: One of the two mothers


studied, a vegan, had a higher proportion of unsaturated fatty acids compared to the other mother who consumed a mixed diet (87% vs 71 %). These preliminary results suggest that 13C MRS


might be used to perform longitudinal studies of different influences on the composition of adipose tissue in infants. 1 Magnetic Resonance in Medicine, 1992:27:97-106 ARTICLE PDF AUTHOR


INFORMATION AUTHORS AND AFFILIATIONS * David Edwards. Department of Paediatrics and Neonatal Medicine, and the Robert Steiner MR Unit, Royal Postgraduate Medical School, London Don Hanrahan,


 Louise Thomas, Jimmy Bell, Denis Azzopardi, Janet Sargentoni, Maria Barnard, David Bryant & Graeme Bydder Authors * Don Hanrahan View author publications You can also search for this


author inPubMed Google Scholar * Louise Thomas View author publications You can also search for this author inPubMed Google Scholar * Jimmy Bell View author publications You can also search


for this author inPubMed Google Scholar * Denis Azzopardi View author publications You can also search for this author inPubMed Google Scholar * Janet Sargentoni View author publications You


can also search for this author inPubMed Google Scholar * Maria Barnard View author publications You can also search for this author inPubMed Google Scholar * David Bryant View author


publications You can also search for this author inPubMed Google Scholar * Graeme Bydder View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND


PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Hanrahan, D., Thomas, L., Bell, J. _et al._ 91 ADIPOSE TISSUE FAT COMPOSITION MEASURED BY CARBON 13 MAGNETIC


RESONANCE SPECTROSCOPY. _Pediatr Res_ 36, 18 (1994). https://doi.org/10.1203/00006450-199407000-00091 Download citation * Issue Date: 01 July 1994 * DOI:


https://doi.org/10.1203/00006450-199407000-00091 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is


not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative