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We studied prealbumin, albumin, IgF1 or IgF1 binding protein as indicators of the adequacy of nutrition in children. Sufficient data about these proteins exist in adults but not children.
Methods: Children admited to the PICU were selected after parental consent. Patients' demographics as well as serum prealbumin, albumin, IgF1 and IgF1 binding protein at baseline, days 3, 5,
7 and 10 were recorded. Base line data were recorded at the day nutrition was started. Total dietary intake was ordered by the primary clinician. Data were analyzed using the statistical
software Statistics. Results: Fourteen children were studied. The age ranged from 2 months-15 years. Mean caloric intake increased from 30 to 57 Kcal/Kg during study period. The mean (±SD)
of albumin, prealbumin, IgF1 and IgF1 binding proteins are shown inTable 1. There was no correlation between any of these proteins with daily caloric intake. There was a trend for increased
serum levels of these proteins but none was statistically significant. Conclusions: Our study failed to support the idea of serum prealbumin, IgF1, IgF1 binding protein and albumin as
markers of nutritional status in children. This study was funded by Beckman Instruments.
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