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ABSTRACT BACKGROUND AND AIMS: New lipid emulsions containing fish oil (FO) have recently became available and they could be proven to be a good source of Arachidonic Acid (ARA) and
Docosahexaenoic Acid (DHA). We compared in preterms the impact of 2 FO containing lipid emulsions and 3 conventional preparations on plasma phospholipid fatty acids (PLFA) status. METHODS:
Seventyfive preterms < 1250g were randomized (15 in each groups) to receive PN with MS (50%MCT,50%soy),OS (80%olive,20%soy), SO (100%soy),FMS (10%FO,50%MCT,40%soy) and FOMS
(15%FO,25%olive,30%MCT,30%soy). The IV lipid intake was increased in a stepwise fashion to 2,5 g•kg-1•d-1 by PN d7. All infants were on minimal enteral feeding. Plasma PLFA were determined
at d7. RESULTS: ARA and DHA intakes (mg•kg-1•d-1) on PN d7 are in table 2. ARA, EPA and DHA of plasma PL (Mol%) on PN d7 are in table 2. Table 1* CONCLUSION: Both the 10% and 15% FO
containing emulsions ensured intrauterine DHA intakes. Plasma ARA PL was lower,Eicosapentaenoic Acid (EPA) and DHA higher in FO groups compared with the standards. The potential benefits on
neurodevelopment and on inflammation need large randomized clinical trials. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Neonatology, Polytechnical University of Marche, Ancona
R D'Ascenzo, S Savini, G Serpentini, I Burattini, A Bartoli, C Biagetti, M P Bellagamba, F Staffolani & V P Carnielli * DMCCP, Pediatric Hospital “Bambino Gesù”, Rome, Italy P E
Cogo Authors * R D'Ascenzo View author publications You can also search for this author inPubMed Google Scholar * S Savini View author publications You can also search for this author
inPubMed Google Scholar * G Serpentini View author publications You can also search for this author inPubMed Google Scholar * I Burattini View author publications You can also search for
this author inPubMed Google Scholar * A Bartoli View author publications You can also search for this author inPubMed Google Scholar * C Biagetti View author publications You can also search
for this author inPubMed Google Scholar * M P Bellagamba View author publications You can also search for this author inPubMed Google Scholar * F Staffolani View author publications You can
also search for this author inPubMed Google Scholar * P E Cogo View author publications You can also search for this author inPubMed Google Scholar * V P Carnielli View author publications
You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE D'Ascenzo, R., Savini, S., Serpentini,
G. _et al._ New Lipid Emulsions for the PN of Preterm Infant: Impact on Ara, Epa and Dha Status. _Pediatr Res_ 70 (Suppl 5), 81 (2011). https://doi.org/10.1038/pr.2011.306 Download citation
* Issue Date: November 2011 * DOI: https://doi.org/10.1038/pr.2011.306 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link
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