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ABSTRACT OBJECTIVE Determine the significance of urinary tract infection (UTI) as a cause of late onset sepsis (LOS) in very low birth weight (VLBW) infants in the Neonatal Intensive Care
Unit (NICU). STUDY DESIGN Analysis of blood, cerebrospinal fluid and urine culture results in VLBW infants >72-h old, admitted to the Georgetown University Hospital NICU between 2005 and
2015. RESULT Of 527 VLBW infants, 297 (56.4%) underwent 911 evaluations for LOS; only one-third included urine cultures. UTI was diagnosed in 8.5% of VLBW infants (range 2–15.9%) and in
13.8% of infants weighing < 1000 g at birth. Gram-negative infections predominated. Concomitant blood cultures were negative in 96% of infants. UTI was more common than bloodstream
infection by 2015. CONCLUSION UTI is a significant cause of infection in VLBW infants. Urine culture should be included in all LOS evaluations in order to facilitate accurate diagnosis and
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our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS URINARY TRACT INFECTIONS IN VERY PREMATURE NEONATES: THE DEFINITION DILEMMA Article 29 March 2024 TREATMENT OF
POSITIVE URINE CULTURES IN THE NEONATAL INTENSIVE CARE UNIT: A GUIDELINE TO REDUCE ANTIBIOTIC UTILIZATION Article 14 May 2021 EARLY-ONSET SEPSIS IN TERM INFANTS ADMITTED TO NEONATAL
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AFFILIATIONS * Division of Neonatology, Medstar Georgetown University Hospital, Washington, DC, USA Caitlin M. Drumm & Jayashree Ramasethu * Department of Pediatrics, Medstar Georgetown
University Hospital, Washington, DC, USA Javedan N. Siddiqui * Department of Biostatistics and Biomedical Informatics, Medstar Health Research Institute, Hyattsville, MD, USA Sameer Desale
Authors * Caitlin M. Drumm View author publications You can also search for this author inPubMed Google Scholar * Javedan N. Siddiqui View author publications You can also search for this
author inPubMed Google Scholar * Sameer Desale View author publications You can also search for this author inPubMed Google Scholar * Jayashree Ramasethu View author publications You can
also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Caitlin M. Drumm. ETHICS DECLARATIONS CONFLICT OF INTEREST The authors declare that they have no
conflict of interest. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Drumm, C.M., Siddiqui, J.N., Desale, S. _et al._ Urinary tract infection is common
in VLBW infants. _J Perinatol_ 39, 80–85 (2019). https://doi.org/10.1038/s41372-018-0226-4 Download citation * Received: 13 June 2018 * Revised: 16 August 2018 * Accepted: 21 August 2018 *
Published: 12 September 2018 * Issue Date: January 2019 * DOI: https://doi.org/10.1038/s41372-018-0226-4 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this
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