A guide to naming eukaryotic circular rnas

A guide to naming eukaryotic circular rnas

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Alternative splicing of eukaryotic messenger RNA transcripts often leads to the production of several mature RNAs — including linear RNAs and circular RNAs (circRNAs) — from a single gene


locus. The names given to circRNAs are often ambiguous and lack consistency across studies. This Comment calls on the community to embrace a common nomenclature for naming circRNAs to ensure


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AFFILIATIONS * State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese


Academy of Sciences, Chinese Academy of Sciences, Shanghai, China Ling-Ling Chen * Institute of Biochemistry, Faculty of Biology and Chemistry, Justus Liebig University of Giessen, Giessen,


Germany Albrecht Bindereif * Department of Biology and Biotechnologies ‘Charles Darwin’ and IIT Center for Life Nano- & Neuro-Science@Sapienza, Sapienza University of Rome, Rome, Italy


Irene Bozzoni * Center for Personal Dynamic Regulomes, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA Howard Y. Chang * Integrative Program in Biological and Genome


Sciences, University of North Carolina, Chapel Hill, NC, USA A. Gregory Matera * Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National


Institutes of Health, Baltimore, MD, USA Myriam Gorospe * Interdisciplinary Nanoscience Center (iNANO), Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark


Thomas B. Hansen & Jørgen Kjems * Center for Molecular Medicine, Children’s Hospital, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, International Laboratory of


Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China Xu-Kai Ma & Li Yang * Temasek Life Sciences Laboratory, 1 Research Link National


University of Singapore, Singapore, Singapore Jun Wei Pek * Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Hemholtz Association, Berlin,


Germany Nikolaus Rajewsky * Department of Biochemistry, Stanford University, Stanford, CA, USA Julia Salzman * Verna and Marrs McLean Department of Biochemistry and Molecular Biology,


Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA Jeremy E. Wilusz * Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China Fangqing Zhao


Authors * Ling-Ling Chen View author publications You can also search for this author inPubMed Google Scholar * Albrecht Bindereif View author publications You can also search for this


author inPubMed Google Scholar * Irene Bozzoni View author publications You can also search for this author inPubMed Google Scholar * Howard Y. Chang View author publications You can also


search for this author inPubMed Google Scholar * A. Gregory Matera View author publications You can also search for this author inPubMed Google Scholar * Myriam Gorospe View author


publications You can also search for this author inPubMed Google Scholar * Thomas B. Hansen View author publications You can also search for this author inPubMed Google Scholar * Jørgen


Kjems View author publications You can also search for this author inPubMed Google Scholar * Xu-Kai Ma View author publications You can also search for this author inPubMed Google Scholar *


Jun Wei Pek View author publications You can also search for this author inPubMed Google Scholar * Nikolaus Rajewsky View author publications You can also search for this author inPubMed 


Google Scholar * Julia Salzman View author publications You can also search for this author inPubMed Google Scholar * Jeremy E. Wilusz View author publications You can also search for this


author inPubMed Google Scholar * Li Yang View author publications You can also search for this author inPubMed Google Scholar * Fangqing Zhao View author publications You can also search for


this author inPubMed Google Scholar CORRESPONDING AUTHORS Correspondence to Ling-Ling Chen, Jeremy E. Wilusz or Li Yang. ETHICS DECLARATIONS COMPETING INTERESTS J.E.W. is a consultant for


Laronde. H.Y.C. is a co-founder of Orbital Therapeutics. The other authors declare no competing interests. PEER REVIEW PEER REVIEW INFORMATION _Nature Cell Biology_ thanks Igor Ulitsky,


Shenglin Huang, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS


ARTICLE Chen, LL., Bindereif, A., Bozzoni, I. _et al._ A guide to naming eukaryotic circular RNAs. _Nat Cell Biol_ 25, 1–5 (2023). https://doi.org/10.1038/s41556-022-01066-9 Download


citation * Published: 19 January 2023 * Issue Date: January 2023 * DOI: https://doi.org/10.1038/s41556-022-01066-9 SHARE THIS ARTICLE Anyone you share the following link with will be able to


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