Is representation enough or should we be targeting equitable inclusion?

Is representation enough or should we be targeting equitable inclusion?

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To achieve health equity, we advocate for the overrepresentation of particular racial and ethnic minority groups so that analyses of group-specific treatment effects can be optimally powered. A paradigm shift is needed across multiple stakeholders, as well as in the engagement of community programmes, the role of investigators from racial and ethnic minority backgrounds and clinical trial regulations. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Owens-Walton, J., Williams, C., Rompré-Brodeur, A., Pinto, P. A. & Ball, M. W. Minority enrollment in phase ii and iii clinical trials in urologic oncology. _J. Clin. Oncol._ https://doi.org/10.1200/JCO.21.01885 (2022). Article  PubMed  Google Scholar  * National Cancer Institute. Surveillance, Epidemiology, End Results Program. Number of Persons by Race and Hispanic Ethnicity for SEER Participants (2020 Census Data), https://seer.cancer.gov/registries/data.html (accessed 17 March 2022). * Borno, H. T. et al. How current reporting practices may mask differences: a call for examining cancer-specific demographic enrollment patterns in cancer treatment clinical trials. _Contemp. Clin. Trials Commun._ 16, 100476 (2019). Article  Google Scholar  * Anderson, A. & Griffith, D. M. Measuring the Trustworthiness of Health Care Organizations and Systems. _Milbank Q._ https://doi.org/10.1111/1468-0009.12564 (2022). Article  PubMed  Google Scholar  * Jones, L. & Wells, K. Strategies for academic and clinician engagement in community-participatory partnered research. _J. Am. Med. Assoc._ 297, 407–410 (2007). Article  CAS  Google Scholar  * NMF. NMF Diversity in Clinical Trials Research Program, https://nmfonline.org/scholarships-programs/diversity-in-research/clinical-trials-research/ (accessed 17 March 2022). * Borno, H. T. et al. Implementation of a multisite financial reimbursement program in cancer clinical trials integrated with patient navigation: a pilot randomized clinical trial. _JCO Oncol. Pract._ https://doi.org/10.1200/OP.21.00328 (2022). Article  PubMed  PubMed Central  Google Scholar  * Strauss, D. H., White, S. A. & Bierer, B. E. Justice, diversity, and research ethics review. _Science_ 371, 1209–1211 (2021). Article  CAS  Google Scholar  * McCaskill-Stevens, W., McKinney, M. M., Whitman, C. G. & Minasian, L. M. Increasing minority participation in cancer clinical trials: the minority-based community clinical oncology program experience. _J. Clin. Oncol._ 23, 5247–5254 (2005). Article  Google Scholar  * Borno, H. T. et al. Integration of electronic pathology reporting with clinical trial matching for advanced prostate cancer. _Urol Oncol._ 39, 494.e7–494.e14 (2021). Article  Google Scholar  Download references ACKNOWLEDGEMENTS Funding was provided in part by the Memorial Sloan Kettering Cancer Center Support Grant (P30 CA008748-50). AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA Scarlett Lin Gomez * Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA Scarlett Lin Gomez * Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA Chiaojung Jillian Tsai Authors * Scarlett Lin Gomez View author publications You can also search for this author inPubMed Google Scholar * Chiaojung Jillian Tsai View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Scarlett Lin Gomez. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. ADDITIONAL INFORMATION RELATED LINKS THE NORTH AMERICAN ASSOCIATION OF CENTRAL CANCER REGISTRIES: https://www.naaccr.org/ THE NCI COMMUNITY ONCOLOGY RESEARCH PROGRAM: https://ncorp.cancer.gov/ RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gomez, S.L., Tsai, C.J. Is representation enough or should we be targeting equitable inclusion?. _Nat Rev Clin Oncol_ 19, 429–430 (2022). https://doi.org/10.1038/s41571-022-00635-z Download citation * Published: 11 April 2022 * Issue Date: July 2022 * DOI: https://doi.org/10.1038/s41571-022-00635-z SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

To achieve health equity, we advocate for the overrepresentation of particular racial and ethnic minority groups so that analyses of group-specific treatment effects can be optimally


powered. A paradigm shift is needed across multiple stakeholders, as well as in the engagement of community programmes, the role of investigators from racial and ethnic minority backgrounds


and clinical trial regulations. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your


institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Learn more Subscribe to this journal


Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices


may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support


REFERENCES * Owens-Walton, J., Williams, C., Rompré-Brodeur, A., Pinto, P. A. & Ball, M. W. Minority enrollment in phase ii and iii clinical trials in urologic oncology. _J. Clin.


Oncol._ https://doi.org/10.1200/JCO.21.01885 (2022). Article  PubMed  Google Scholar  * National Cancer Institute. Surveillance, Epidemiology, End Results Program. Number of Persons by Race


and Hispanic Ethnicity for SEER Participants (2020 Census Data), https://seer.cancer.gov/registries/data.html (accessed 17 March 2022). * Borno, H. T. et al. How current reporting practices


may mask differences: a call for examining cancer-specific demographic enrollment patterns in cancer treatment clinical trials. _Contemp. Clin. Trials Commun._ 16, 100476 (2019). Article 


Google Scholar  * Anderson, A. & Griffith, D. M. Measuring the Trustworthiness of Health Care Organizations and Systems. _Milbank Q._ https://doi.org/10.1111/1468-0009.12564 (2022).


Article  PubMed  Google Scholar  * Jones, L. & Wells, K. Strategies for academic and clinician engagement in community-participatory partnered research. _J. Am. Med. Assoc._ 297, 407–410


(2007). Article  CAS  Google Scholar  * NMF. NMF Diversity in Clinical Trials Research Program, https://nmfonline.org/scholarships-programs/diversity-in-research/clinical-trials-research/


(accessed 17 March 2022). * Borno, H. T. et al. Implementation of a multisite financial reimbursement program in cancer clinical trials integrated with patient navigation: a pilot randomized


clinical trial. _JCO Oncol. Pract._ https://doi.org/10.1200/OP.21.00328 (2022). Article  PubMed  PubMed Central  Google Scholar  * Strauss, D. H., White, S. A. & Bierer, B. E. Justice,


diversity, and research ethics review. _Science_ 371, 1209–1211 (2021). Article  CAS  Google Scholar  * McCaskill-Stevens, W., McKinney, M. M., Whitman, C. G. & Minasian, L. M.


Increasing minority participation in cancer clinical trials: the minority-based community clinical oncology program experience. _J. Clin. Oncol._ 23, 5247–5254 (2005). Article  Google


Scholar  * Borno, H. T. et al. Integration of electronic pathology reporting with clinical trial matching for advanced prostate cancer. _Urol Oncol._ 39, 494.e7–494.e14 (2021). Article 


Google Scholar  Download references ACKNOWLEDGEMENTS Funding was provided in part by the Memorial Sloan Kettering Cancer Center Support Grant (P30 CA008748-50). AUTHOR INFORMATION AUTHORS


AND AFFILIATIONS * Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA Scarlett Lin Gomez * Helen Diller Family Comprehensive Cancer Center,


University of California, San Francisco, CA, USA Scarlett Lin Gomez * Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA Chiaojung Jillian Tsai


Authors * Scarlett Lin Gomez View author publications You can also search for this author inPubMed Google Scholar * Chiaojung Jillian Tsai View author publications You can also search for


this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Scarlett Lin Gomez. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. ADDITIONAL


INFORMATION RELATED LINKS THE NORTH AMERICAN ASSOCIATION OF CENTRAL CANCER REGISTRIES: https://www.naaccr.org/ THE NCI COMMUNITY ONCOLOGY RESEARCH PROGRAM: https://ncorp.cancer.gov/ RIGHTS


AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gomez, S.L., Tsai, C.J. Is representation enough or should we be targeting equitable inclusion?. _Nat Rev Clin


Oncol_ 19, 429–430 (2022). https://doi.org/10.1038/s41571-022-00635-z Download citation * Published: 11 April 2022 * Issue Date: July 2022 * DOI: https://doi.org/10.1038/s41571-022-00635-z


SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to


clipboard Provided by the Springer Nature SharedIt content-sharing initiative