Resisting antimicrobial resistance

Resisting antimicrobial resistance

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To control antimicrobial resistance (AMR) will require approaches to develop, share and preserve antibiotics that are scaled to the scientific, economic and ethical dimensions of the crisis. The three cooperative, interdisciplinary, international councils proposed here exemplify what this will require. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * ANTIMICROBIAL RESISTANCE IN A CHANGING CLIMATE: A ONE HEALTH APPROACH FOR ADAPTATION AND MITIGATION * Muhammad Yasir Alhassan *  & Abdulhamid Abdullahi Ahmad _Bulletin of the National Research Centre_ Open Access 18 April 2025 * ADOPTIVE CELL TRANSFER OF PIEZO-ACTIVATED MACROPHAGE RESCUES IMMUNOSUPPRESSED RODENTS FROM LIFE-THREATING BACTERIAL INFECTIONS * Xiaoyi Liu * , Wenxiu Xu *  … Jianhua Li _Nature Communications_ Open Access 04 February 2025 * ACCURATE AND FAST IDENTIFICATION OF MINIMALLY PREPARED BACTERIA PHENOTYPES USING RAMAN SPECTROSCOPY ASSISTED BY MACHINE LEARNING * Benjamin Lundquist Thomsen * , Jesper B. Christensen *  … Mikael Lassen _Scientific Reports_ Open Access 30 September 2022 ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $29.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Roope, L. S. J. et al. The challenge of antimicrobial resistance: what economics can contribute. _Science_ 364, eaau4679 (2019). Article  CAS  Google Scholar  * The Review on Antimicrobial Resistance. _Tackling drug-resistant infections globally: final report and recommendations_. https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf (2016). * Nathan, C. & Cars, O. Antibiotic resistance — problems, progress, and prospects. _N. Engl. J. Med._ 371, 1761–1763 (2014). Article  Google Scholar  * Laxminarayan, R., Sridhar, D., Blaser, M., Wang, M. & Woolhouse, M. Achieving global targets for antimicrobial resistance. _Science_ 353, 874–875 (2016). Article  CAS  Google Scholar  * Nathan, C. Aligning pharmaceutical innovation with medical need. _Nat. Med._ 13, 304–308 (2007). Article  CAS  Google Scholar  * Nielsen, T. B., Brass, E. P., Gilbert, D. N., Bartlett, J. G. & Spellberg, B. Sustainable discovery and development of antibiotics - is a nonprofit approach the future? _N. Engl. J. Med._ 381, 503–505 (2019). Article  Google Scholar  * Outterson, K. et al. Delinking investment in antibiotic research and development from sales revenues: the challenges of transforming a promising idea into reality. _PLoS Med._ 13, e1002043 (2016). Article  Google Scholar  * Årdal, C. et al. _Drive-AB Report. Revitalizing the antibiotic pipeline_. http://drive-ab.eu/wp-content/uploads/2018/01/DRIVE-AB-Final-Report-Jan2018.pdf (2018). * Barbier, E. Sustainability: tax ‘societal ills’ to save the planet. _Nature_ 483, 30 (2012). Article  CAS  Google Scholar  * Nathan, C. F. Cooperative development of antimicrobials: looking back to look ahead. _Nat. Rev. Microbiol._ 13, 651–657 (2015). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Weill Cornell Medicine, New York, USA Carl Nathan Authors * Carl Nathan View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Carl Nathan. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing interests. ADDITIONAL INFORMATION RELATED LINKS COMBATING ANTIBIOTIC RESISTANT BACTERIA BIOPHARMACEUTICAL ACCELERATOR (CARB-X): https://carb-x.org GLOBAL ANTIBIOTIC RESEARCH AND DEVELOPMENT PARTNERSHIP (GARDP): https://www.gardp.org RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Nathan, C. Resisting antimicrobial resistance. _Nat Rev Microbiol_ 18, 259–260 (2020). https://doi.org/10.1038/s41579-020-0348-5 Download citation * Published: 16 April 2020 * Issue Date: May 2020 * DOI: https://doi.org/10.1038/s41579-020-0348-5 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

To control antimicrobial resistance (AMR) will require approaches to develop, share and preserve antibiotics that are scaled to the scientific, economic and ethical dimensions of the crisis.


The three cooperative, interdisciplinary, international councils proposed here exemplify what this will require. Access through your institution Buy or subscribe This is a preview of


subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * ANTIMICROBIAL RESISTANCE IN A CHANGING CLIMATE: A ONE HEALTH APPROACH FOR


ADAPTATION AND MITIGATION * Muhammad Yasir Alhassan *  & Abdulhamid Abdullahi Ahmad _Bulletin of the National Research Centre_ Open Access 18 April 2025 * ADOPTIVE CELL TRANSFER OF


PIEZO-ACTIVATED MACROPHAGE RESCUES IMMUNOSUPPRESSED RODENTS FROM LIFE-THREATING BACTERIAL INFECTIONS * Xiaoyi Liu * , Wenxiu Xu *  … Jianhua Li _Nature Communications_ Open Access 04


February 2025 * ACCURATE AND FAST IDENTIFICATION OF MINIMALLY PREPARED BACTERIA PHENOTYPES USING RAMAN SPECTROSCOPY ASSISTED BY MACHINE LEARNING * Benjamin Lundquist Thomsen * , Jesper B.


Christensen *  … Mikael Lassen _Scientific Reports_ Open Access 30 September 2022 ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get


Nature+, our best-value online-access subscription $29.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only


$17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout


ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Roope, L. S. J. et al. The challenge of antimicrobial


resistance: what economics can contribute. _Science_ 364, eaau4679 (2019). Article  CAS  Google Scholar  * The Review on Antimicrobial Resistance. _Tackling drug-resistant infections


globally: final report and recommendations_. https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf (2016). * Nathan, C. & Cars, O. Antibiotic resistance —


problems, progress, and prospects. _N. Engl. J. Med._ 371, 1761–1763 (2014). Article  Google Scholar  * Laxminarayan, R., Sridhar, D., Blaser, M., Wang, M. & Woolhouse, M. Achieving


global targets for antimicrobial resistance. _Science_ 353, 874–875 (2016). Article  CAS  Google Scholar  * Nathan, C. Aligning pharmaceutical innovation with medical need. _Nat. Med._ 13,


304–308 (2007). Article  CAS  Google Scholar  * Nielsen, T. B., Brass, E. P., Gilbert, D. N., Bartlett, J. G. & Spellberg, B. Sustainable discovery and development of antibiotics - is a


nonprofit approach the future? _N. Engl. J. Med._ 381, 503–505 (2019). Article  Google Scholar  * Outterson, K. et al. Delinking investment in antibiotic research and development from sales


revenues: the challenges of transforming a promising idea into reality. _PLoS Med._ 13, e1002043 (2016). Article  Google Scholar  * Årdal, C. et al. _Drive-AB Report. Revitalizing the


antibiotic pipeline_. http://drive-ab.eu/wp-content/uploads/2018/01/DRIVE-AB-Final-Report-Jan2018.pdf (2018). * Barbier, E. Sustainability: tax ‘societal ills’ to save the planet. _Nature_


483, 30 (2012). Article  CAS  Google Scholar  * Nathan, C. F. Cooperative development of antimicrobials: looking back to look ahead. _Nat. Rev. Microbiol._ 13, 651–657 (2015). Article  CAS 


Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Weill Cornell Medicine, New York, USA Carl Nathan Authors * Carl Nathan View author publications You can


also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Carl Nathan. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing interests.


ADDITIONAL INFORMATION RELATED LINKS COMBATING ANTIBIOTIC RESISTANT BACTERIA BIOPHARMACEUTICAL ACCELERATOR (CARB-X): https://carb-x.org GLOBAL ANTIBIOTIC RESEARCH AND DEVELOPMENT PARTNERSHIP


(GARDP): https://www.gardp.org RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Nathan, C. Resisting antimicrobial resistance. _Nat Rev Microbiol_ 18,


259–260 (2020). https://doi.org/10.1038/s41579-020-0348-5 Download citation * Published: 16 April 2020 * Issue Date: May 2020 * DOI: https://doi.org/10.1038/s41579-020-0348-5 SHARE THIS


ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard


Provided by the Springer Nature SharedIt content-sharing initiative