Resisting antimicrobial resistance

Resisting antimicrobial resistance

Play all audios:

Loading...

To control antimicrobial resistance (AMR) will require approaches to develop, share and preserve antibiotics that are scaled to the scientific, economic and ethical dimensions of the crisis. The three cooperative, interdisciplinary, international councils proposed here exemplify what this will require. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Roope, L. S. J. et al. The challenge of antimicrobial resistance: what economics can contribute. _Science_ 364, eaau4679 (2019). Article  CAS  Google Scholar  * The Review on Antimicrobial Resistance. _Tackling drug-resistant infections globally: final report and recommendations_. https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf (2016). * Nathan, C. & Cars, O. Antibiotic resistance — problems, progress, and prospects. _N. Engl. J. Med._ 371, 1761–1763 (2014). Article  Google Scholar  * Laxminarayan, R., Sridhar, D., Blaser, M., Wang, M. & Woolhouse, M. Achieving global targets for antimicrobial resistance. _Science_ 353, 874–875 (2016). Article  CAS  Google Scholar  * Nathan, C. Aligning pharmaceutical innovation with medical need. _Nat. Med._ 13, 304–308 (2007). Article  CAS  Google Scholar  * Nielsen, T. B., Brass, E. P., Gilbert, D. N., Bartlett, J. G. & Spellberg, B. Sustainable discovery and development of antibiotics - is a nonprofit approach the future? _N. Engl. J. Med._ 381, 503–505 (2019). Article  Google Scholar  * Outterson, K. et al. Delinking investment in antibiotic research and development from sales revenues: the challenges of transforming a promising idea into reality. _PLoS Med._ 13, e1002043 (2016). Article  Google Scholar  * Årdal, C. et al. _Drive-AB Report. Revitalizing the antibiotic pipeline_. http://drive-ab.eu/wp-content/uploads/2018/01/DRIVE-AB-Final-Report-Jan2018.pdf (2018). * Barbier, E. Sustainability: tax ‘societal ills’ to save the planet. _Nature_ 483, 30 (2012). Article  CAS  Google Scholar  * Nathan, C. F. Cooperative development of antimicrobials: looking back to look ahead. _Nat. Rev. Microbiol._ 13, 651–657 (2015). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Weill Cornell Medicine, New York, USA Carl Nathan Authors * Carl Nathan View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Carl Nathan. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing interests. ADDITIONAL INFORMATION RELATED LINKS COMBATING ANTIBIOTIC RESISTANT BACTERIA BIOPHARMACEUTICAL ACCELERATOR (CARB-X): https://carb-x.org GLOBAL ANTIBIOTIC RESEARCH AND DEVELOPMENT PARTNERSHIP (GARDP): https://www.gardp.org RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Nathan, C. Resisting antimicrobial resistance. _Nat Rev Microbiol_ 18, 259–260 (2020). https://doi.org/10.1038/s41579-020-0348-5 Download citation * Published: 16 April 2020 * Issue Date: May 2020 * DOI: https://doi.org/10.1038/s41579-020-0348-5 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

To control antimicrobial resistance (AMR) will require approaches to develop, share and preserve antibiotics that are scaled to the scientific, economic and ethical dimensions of the crisis.


The three cooperative, interdisciplinary, international councils proposed here exemplify what this will require. Access through your institution Buy or subscribe This is a preview of


subscription content, access via your institution ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value


online-access subscription $32.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more


Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS:


* Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Roope, L. S. J. et al. The challenge of antimicrobial resistance: what economics


can contribute. _Science_ 364, eaau4679 (2019). Article  CAS  Google Scholar  * The Review on Antimicrobial Resistance. _Tackling drug-resistant infections globally: final report and


recommendations_. https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf (2016). * Nathan, C. & Cars, O. Antibiotic resistance — problems, progress, and


prospects. _N. Engl. J. Med._ 371, 1761–1763 (2014). Article  Google Scholar  * Laxminarayan, R., Sridhar, D., Blaser, M., Wang, M. & Woolhouse, M. Achieving global targets for


antimicrobial resistance. _Science_ 353, 874–875 (2016). Article  CAS  Google Scholar  * Nathan, C. Aligning pharmaceutical innovation with medical need. _Nat. Med._ 13, 304–308 (2007).


Article  CAS  Google Scholar  * Nielsen, T. B., Brass, E. P., Gilbert, D. N., Bartlett, J. G. & Spellberg, B. Sustainable discovery and development of antibiotics - is a nonprofit


approach the future? _N. Engl. J. Med._ 381, 503–505 (2019). Article  Google Scholar  * Outterson, K. et al. Delinking investment in antibiotic research and development from sales revenues:


the challenges of transforming a promising idea into reality. _PLoS Med._ 13, e1002043 (2016). Article  Google Scholar  * Årdal, C. et al. _Drive-AB Report. Revitalizing the antibiotic


pipeline_. http://drive-ab.eu/wp-content/uploads/2018/01/DRIVE-AB-Final-Report-Jan2018.pdf (2018). * Barbier, E. Sustainability: tax ‘societal ills’ to save the planet. _Nature_ 483, 30


(2012). Article  CAS  Google Scholar  * Nathan, C. F. Cooperative development of antimicrobials: looking back to look ahead. _Nat. Rev. Microbiol._ 13, 651–657 (2015). Article  CAS  Google


Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Weill Cornell Medicine, New York, USA Carl Nathan Authors * Carl Nathan View author publications You can also


search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Carl Nathan. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing interests.


ADDITIONAL INFORMATION RELATED LINKS COMBATING ANTIBIOTIC RESISTANT BACTERIA BIOPHARMACEUTICAL ACCELERATOR (CARB-X): https://carb-x.org GLOBAL ANTIBIOTIC RESEARCH AND DEVELOPMENT PARTNERSHIP


(GARDP): https://www.gardp.org RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Nathan, C. Resisting antimicrobial resistance. _Nat Rev Microbiol_ 18,


259–260 (2020). https://doi.org/10.1038/s41579-020-0348-5 Download citation * Published: 16 April 2020 * Issue Date: May 2020 * DOI: https://doi.org/10.1038/s41579-020-0348-5 SHARE THIS


ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard


Provided by the Springer Nature SharedIt content-sharing initiative