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Access through your institution Buy or subscribe A better understanding of the pathways that define treatment response may enable more targeted treatment strategies for patients with lupus
nephritis. New analyses of protocol kidney biopsy samples have now identified transcripts that differentiate clinically complete responders from non-responders. At flare, transcripts
encoding integrins, neutrophils, chemokines, T cells and leukocyte adhesion molecules differentiated non-responders from responders, whereas after treatment, non-responders were
differentiated by differences in monocyte, extracellular matrix, interferon, complement and T cell transcripts. This is a preview of subscription content, access via your institution ACCESS
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FAQs * Contact customer support REFERENCES ORIGINAL ARTICLE * Parikh, S. V. et al. Molecular profiling of kidney compartments from serial biopsies differentiate treatment responders from
non-responders in lupus nephritis. _Kidney Int._ https://doi.org/10.1016/j.kint.2022.05.033 (2022) Article PubMed Google Scholar Download references AUTHOR INFORMATION AUTHORS AND
AFFILIATIONS * Nature Reviews Nephrology http://www.nature.com/nrneph Susan J. Allison Authors * Susan J. Allison View author publications You can also search for this author inPubMed Google
Scholar CORRESPONDING AUTHOR Correspondence to Susan J. Allison. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Allison, S.J. Determining treatment
response in lupus nephritis. _Nat Rev Nephrol_ 18, 543 (2022). https://doi.org/10.1038/s41581-022-00611-x Download citation * Published: 25 July 2022 * Issue Date: September 2022 * DOI:
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