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Access through your institution Buy or subscribe Changes in synchronization of activity across brain regions accompany conversion from mild cognitive impairment (MCI) to Alzheimer disease
(AD), according to a new study published in _Brain_. The findings could lead to better prediction of outcome for patients with MCI. Pusil and colleagues performed a baseline MEG recording
followed by 3 years of cognitive and clinical assessments in 145 patients with MCI. Twenty-seven patients progressed to a diagnosis of probable AD during the 3 years and underwent a second
MEG recording. Patients who did not progress to AD underwent repeat MEG at the end of the study. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access
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support REFERENCES ORIGINAL ARTICLE * Pusil, S. et al. Hypersynchronization in mild cognitive impairment: the ‘X’ model. _Brain_ https://doi.org/10.1093/brain/awz320 (2019) Article PubMed
Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Nature Reviews Neurology http://www.nature.com/nrneurol/ Sarah Lemprière Authors * Sarah Lemprière View
author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Sarah Lemprière. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT
THIS ARTICLE CITE THIS ARTICLE Lemprière, S. Changes in network synchronization herald Alzheimer Disease. _Nat Rev Neurol_ 15, 686–687 (2019). https://doi.org/10.1038/s41582-019-0288-8
Download citation * Published: 06 November 2019 * Issue Date: December 2019 * DOI: https://doi.org/10.1038/s41582-019-0288-8 SHARE THIS ARTICLE Anyone you share the following link with will
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